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Keywords: Mammalian target of rapamycin
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Nephron Experimental Nephrology (2014) 128 (3-4): 98–110.
Published Online: 06 December 2014
... by increases in mammalian target of rapamycin (mTOR) C1 activity and p62/SQSTM1 expression. These results led us to propose that AMPK and autophagy are insufficient to properly counter the cellular insults in ischemia-reperfusion. Agonist induction of AMPK activity with AICAR or metformin increased...