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Keywords: Interstitial fibrosis
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Journal Articles

Uninephrectomy of Diabetic OVE26 Mice Greatly Accelerates Albuminuria, Fibrosis, Inflammatory Cell Infiltration and Changes in Gene Expression

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Topic Article Package: Diabetes , Nephrology
Shirong Zheng, Yun Huang, Lu Yang, Teresa Chen, Jianxiang Xu, Paul N. Epstein
Journal: Nephron Experimental Nephrology
Nephron Experimental Nephrology (2011) 119 (1): e21–e32.
https://doi.org/10.1159/000327586
Published Online: 09 June 2011
...Shirong Zheng; Yun Huang; Lu Yang; Teresa Chen; Jianxiang Xu; Paul N. Epstein Background/Aims: OVE26 (OVE) mice provide a valuable model of advanced diabetic nephropathy (DN), but they take 8 months to develop moderate interstitial fibrosis and reduced glomerular filtration rate (GFR). The aim...
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Journal Articles

Low-Dose Darbepoetin α Attenuates Progression of a Mouse Model of Aristolochic Acid Nephropathy through Early Tubular Protection

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Subject Area:
Nephrology
Yuki Hamano, Takahiro Aoki, Ryota Shirai, Megumi Hatano, Ryota Kimura, Makoto Ogawa, Osamu Yokosuka, Shiro Ueda
Journal: Nephron Experimental Nephrology
Nephron Experimental Nephrology (2010) 114 (2): e69–e81.
https://doi.org/10.1159/000256569
Published Online: 07 November 2009
..., interstitial fibrosis and end-stage renal disease. Tubulointerstitial injury was studied in a mouse model of AA nephropathy to determine whether low-dose darbepoetin α (DPO) treatment prevents acute tubular necrosis and interstitial fibrosis. Methods: AA was administered to C3H/He mice intraperitoneally...
View articletitled, Low-Dose Darbepoetin α Attenuates Progression of a Mouse Model of Aristolochic Acid Nephropathy through Early Tubular Protection
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