... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2011 High serum IgA mice IgA nephropathy Polyunsaturated fatty acids Perilla frutescens Transforming growth factor-β Immunoglobulin A nephropathy (IgAN), the most common...

...Joseph C.K. Leung; Loretta Y.Y. Chan; Sydney C.W. Tang; P.C. Tam; John Fenn; Kar Neng Lai Background: IgA nephropathy (IgAN) is characterized by mesangial deposition of polymeric IgA1 (pIgA1), yet the pathogeneic mechanism remains unresolved. In the present study, we examined the glycosylation...

...Patrick H. Maxwell; Yiming Wang IgA nephropathy is the commonest form of glomerulonephritis worldwide, but we still know relatively little about its pathogenesis. Potentially, genetic studies might provide new insights and suggest novel therapeutic approaches to this important cause of chronic...

... between increased renal tissue levels of TGF-β1 and fibronectin has been reported in IgA nephropathy, no data are available on renal tissue expression of Rho proteins. Methods: This study was designed to assess in IgA nephropathy patients the kidney tissue immunohistochemical expression of RhoA, TGF-β1...

... in this article. IgA nephropathy Sairei-to Superoxide dismutase Transforming growth factor-β Connective tissue growth factor Kidney tissues were fixed in 10% neutral-buffered formalin (pH 7.4), embedded in paraffin, and then sections (4 µm) were treated with trichrome staining, which...

... polymorphism of β 3 integrin has been associated with altered platelet functions, cardiovascular complications and the incidence of acute rejection episodes in renal transplantation. We investigated its influence on IgA nephropathy (IgAN), focal segmental glomerulosclerosis (FSGS) and membranous...

...Toshiyuki Imasawa; Yasunori Utsunomiya The pathogenesis of IgA nephropathy (IgAN) is still obscure. In this study, we investigated whether the fundamental pathogenesis of IgAN lies in bone marrow stem cells (BMCs) and whether bone marrow transplantation from normal C57BL/6j (B6) mice can attenuate...