... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2012 Targeted delivery Lupus nephritis Glomerulus T cells NIH CD4+ T cells are important mediators of systemic lupus...

... to in the content or advertisements. 2008 Acute renal failure Vasodilatation Nitric oxide Apoptosis Glomerulus Tubule Afferent arteriole Efferent arteriole Glomerular filtration rate In several experimental studies of septic ARF, global renal blood flow declines after induction of sepsis...

... development, in the healthy adult, and in disease. These studies are encouraging and show that comprehensive molecular profiling of the kidney glomerulus will most likely provide significant new insights into the normal structure and function of the glomerular filter, the molecular mechanisms of glomerular...

... inhibitors Glomerulus Podocyte Hypertrophy Apoptosis Proliferation DNA damage The glomerular visceral epithelial cell, also called the podocyte, has a highly complex cytoarchitecture that determines its elaborate function as a critical component of the glomerular filtration barrier. Podocytes...

.... This review will summarize recent progress in understanding cytoskeletal dynamics in the podocyte and will review modern imaging techniques relevant to studying this area of podocyte biology. Podocyte Cytoskeleton Actin Glomerulus Imaging References 1. Andrews PM, Bates SB: Filamentous...

.... This interaction may regulate transforming growth factor-β (TGF-β) activity. TGF-β is an important progression factor for glomerular diseases. We hypothesized that LTBP-1 and fibrillin-1 are coexpressed in the glomerulus and upregulated during glomerulonephritis. Methods: Acute anti-Thy1.1 glomerulonephritis...

...Caroline B. Marshall; Stuart J. Shankland Globally, glomerular diseases are a leading cause of chronic and end-stage renal disease. In the mature glomerulus, under normal conditions, glomerular cells have a low turnover rate. However, in disease, a variety of pathophysiological stimuli can lead...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2005 Purinergic receptors P2X7 ATP Nephrogenesis Renal tubule Glomerulus Polycystic kidneys Recent data reveals functionally...

... of immunohistochemistry, Western blotting, immunoelectron microscopy and in situ hybridization, we investigated the contribution of different laminin chains and collagen type IV isotypes to the basement membrane thickening and mesangial expansion. We report that exposure of the glomerulus to TGF-β1 in vivo induces...

...Moin A. Saleem The glomerulus is a complex physiological structure that, as well as maintaining a selective filtration barrier, participates in the control of renal blood flow and blood pressure. Recently there has been a surge of interest in the podocyte, as the main player in this functional unit...

... stained with Masson’s trichrome. Since the results were normalized to 1 mg of glomerular proteins, we first verified that the protein content per glomerulus was not altered by the treatment with L -NAME. We found 15.7 ± 1.9 vs. 16.4 ± 1.4 glomeruli per µg protein (n = 10) for controls and rats...

.... 2004 Hyperglycemia Renin-angiotensin system Proximal tubules Glomerulus Apoptosis is a morphologically distinct, programmed form of cell death, characterized by the formation of membrane blebbing, cell shrinkage, chromatin condensation, and internucleosomal DNA fragmentation...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2004 Smads Transforming growth factor-β OLETF Diabetic nephropathy Glomerulus Diabetic...

... available) may provide more effective therapy for kidney disease progression. Myofibroblast differentiation Plasma membrane microdomains Cell phenotype Mesangial cell Glomerulus Glomerulosclerosis Cytoarchitecture Caveoli Focal adhesions Lipid rafts More recently, several papers have...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Glycosaminoglycans Kidney Glomerulus Chronic renal failure Data are presented as mean ± SD. The significance of differences between mean values was determined...

... that the vasoconstrictor effect of angiotensin II on EAs is modulated by prostaglandins produced by the upstream glomerulus. Thus, this may be a mechanism whereby the glomerulus controls its own capillary pressure by releasing prostaglandins and thereby adjusting the resistance of the downstream EA. These varying...

.... Mesangial cells Tubular epithelial cells Glomerulus Oligodeoxynucleotides Glomerulonephritis Interstitial nephritis Antisense oligodeoxynucleotides (AS-ODNs) have recently emerged as potential agents for blocking gene expression [ 1, 2 ]. Specifically, deoxynucleotides are comprised...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cyclin Glomerulus Proliferation Mesangial cell Cell cycle Cell proliferation...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Differential display Kidney Glomerulus Gene expression Congenital...

... in the generation of glomerular injury. The aim of this article is to summarize the potentially beneficial action of TGF-β in the glomerulus and to address its ‘bright side’ in glomerular inflammation. 4 2 1998 1998 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...