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Keywords: Glomerulosclerosis
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Journal Articles
Journal Articles
Subject Area:
Nephrology
Nephron Experimental Nephrology (2013) 124 (3-4): 11–18.
Published Online: 08 January 2014
...Takayuki Okamoto; Satoshi Sasaki; Takeshi Yamazaki; Yasuyuki Sato; Hironobu Ito; Tadashi Ariga Background/Aims: Recent study suggests that activation of parietal epithelial cells (PECs) contributes to pathogenesis of glomerulosclerosis and the activation marker CD44 increases in evolving...
Journal Articles
Subject Area:
Nephrology
Nephron Experimental Nephrology (2011) 119 (Suppl. 1): e1–e5.
Published Online: 10 August 2011
... function Calorie restriction Glomerulosclerosis Cellular senescence Autophagy Telomere Klotho US Census data show that the oldest age groups are the fastest growing segment of the US population, and a similar trend is also seen in European countries and in Japan [ 1 ]. There have been very...
Journal Articles
Subject Area:
Nephrology
Nephron Experimental Nephrology (2011) 119 (Suppl. 1): e6–e10.
Published Online: 10 August 2011
..., microalbuminuria is reversible but becomes fixed with the progression of vascular structural changes including glomerulosclerosis. The prevalence of microalbuminuria increases with age and has been shown to be a marker of widespread microvasculopathy at various levels including cerebral, cardiac and renal...
Journal Articles
Journal Articles
Subject Area:
Nephrology
Nephron Experimental Nephrology (2010) 114 (1): e7–e14.
Published Online: 09 October 2009
... of Tripterygium wilfordii Hook f. Progressive glomerulonephritis Glomerulosclerosis Mesangial lesions Cytokines The chronic phase of progressive glomerulonephritis (GN) both in animal models and in humans is characterized by prolonged glomerulosclerosis, including glomerular infiltration...
Journal Articles
Subject Area:
Nephrology
Nephron Experimental Nephrology (2009) 111 (4): e73–e79.
Published Online: 17 March 2009
...Thiruvur Niranjan; Mariana Murea; Katalin Susztak Podocytes play a key role in the maintenance of the glomerular filtration barrier. Depletion or dysregulative mechanisms of podocytes can lead to the development of glomerulosclerosis. Signaling pathways that control these processes in podocytes...
Journal Articles
Subject Area:
Nephrology
Nephron Experimental Nephrology (2008) 108 (1): e1–e10.
Published Online: 17 December 2007
... compartments, glomerular, tubular and interstitial, showed a positive linear correlation with serum creatinine, proteinuria, glomerulosclerosis score and interstitial fibrosis scores. Using multivariate analysis, immunostainable tubular SCF was a predictor of glomerular sclerosis and immunostainable glomerular...
Journal Articles
Subject Area:
Nephrology
Nephron Experimental Nephrology (2007) 107 (1): e30–e40.
Published Online: 06 August 2007
...Michael R. Bennett; Kimberly A. Czech; Lois J. Arend; David P. Witte; Prasad Devarajan; S. Steven Potter Focal segmental glomerulosclerosis (FSGS) is a major cause of end-stage renal disease. In this report we used laser capture microdissection to purify diseased glomeruli, and microarrays...
Journal Articles
Subject Area:
Nephrology
Nephron Experimental Nephrology (2006) 104 (4): e158–e168.
Published Online: 11 August 2006
.... Glomerulosclerosis was reduced to the extent that a remarkable percentage of glomeruli without sclerosis appeared after treatment. Podocyte number was normalized. Renoprotection of 1D11 was comparable to enalapril. Despite control of blood pressure, in late treatment single agents did not reduce proteinuria...
Journal Articles
Subject Area:
Nephrology
Nephron Experimental Nephrology (2003) 93 (4): e134–e140.
Published Online: 17 November 2004
... and specifically could underlie growth hormone (GH)-induced glomerulosclerosis. The present study investigates the role of GH in the regulation of LDL-r and HMG-CoA reductase mRNA expression in mesangial cells. Mouse mesangial cells were equilibrated in a medium containing 5% lipoprotein-deprived serum (LPDS...
Journal Articles
Subject Area:
Nephrology
Experimental Nephrology (2002) 10 (5-6): 313–319.
Published Online: 09 October 2002
... Mesangial cell Glomerulus Glomerulosclerosis Cytoarchitecture Caveoli Focal adhesions Lipid rafts References 1. Johnson RJ: The glomerular response to injury: Progression or resolution. Kidney Int 1994;45:1769–1782. 2. Sedor JR, Konieczkowski M, Huang S, Gronich JH, Nakazato Y, Gordon...
Journal Articles
Journal Articles
Subject Area:
Nephrology
Experimental Nephrology (2000) 8 (4-5): 181–193.
Published Online: 31 July 2000
... glomerulonephritis, glomerulosclerosis, and tubulointerstitial disease are readily available; however, these depend heavily on the mouse genetic background. Attention to the genetic background and appropriate backcrossing are, therefore, of great importance in the design and interpretation of experimental studies...
Journal Articles
Subject Area:
Nephrology
Experimental Nephrology (2000) 8 (2): 91–96.
Published Online: 15 March 2000
...Christiane van den Branden; Bart Ceyssens; Dirk De Craemer; Pieter De Bleser; Karine Hellemans; Albert Geerts; Dierik Verbeelen Reactive oxygen intermediates play a role in chronic renal injury and glomerulosclerosis. We investigate changes in renal cortex antioxidant enzyme gene expression...
Journal Articles
Subject Area:
Nephrology
Experimental Nephrology (1999) 7 (2): 147–159.
Published Online: 23 April 1999
...Agnes B. Fogo Progressive deterioration of the kidney is common to many renal diseases. The structural injuries which lead to this progressive loss of function consist of focal segmental glomerulosclerosis and tubulointerstitial fibrosis and atrophy. These processes were previously thought...
Journal Articles
Subject Area:
Nephrology
Experimental Nephrology (1998) 6 (1): 28–38.
Published Online: 04 February 1998
... after streptozotocin administration, and kidney morphological evaluation was performed after 4 months of diabetes. We also studied the effect of angiotensin II antagonism on development of renal lesions. Untreated animals developed mild hypertension, proteinuria, and glomerulosclerosis. Induction...
Journal Articles