... in ICGN mice, we conducted a comprehensive gene expression analysis using DNA microarray. Immune-related pathways were markedly altered in ICGN mice kidney as compared with ICR mice. Furthermore, the gene expression level of complement component 1, s subcomponent (C1s) , whose human homologue has been...

...Rajesh Kher; Robert L. Bacallao Genome-wide sequencing and increasing use of microarrays has resulted in the identification of a large number of new genes which may have important functional roles in development and onset of disease. Classical approaches in gene expression studies fall short...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2004 Nitric oxide Superoxide Redox signaling Gene expression Inflammation...

...Michael Rudnicki; Susanne Eder; Gabriele Schratzberger; Bernd Mayer; Timothy W. Meyer; Martin Tonko; Gert Mayer Genome wide gene expression analysis by cDNA microarrays is often limited by minute amounts of starting RNA. We therefore tested an optimized linear RNA amplification protocol using...

... [ 21 ]. Cystinuria Gene expression Nephrolithiasis D-Penicillamine Cystinuria is a hereditary form of nephrolithiasis due to dysfunction of the reabsorptive transport mechanism shared by cystine and dibasic amino acids (ornithine, arginine and lysine) at the luminal brush border...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2004 Oxalate Kidney stone Phospholipase A2 Mitochondria Gene expression Cell death Nephrolithiasis encompasses a family of disorders that culminate in a common...

... expression changes occur in leukocytes that are circulating in patients with renal diseases. In addition, gene expression has been studied in leukocytes activated in vitro by mechanisms that mimic pathogenic events in vivo. The expression levels of genes identified in in vitro studies were compared...

... of parallel processing, robotics, and computer-based informatics, a number of high-throughput methods have been devised. These include DNA microarrays, serial analysis of gene expression, quantitative RT-PCR, differential-display RT-PCR, and massively parallel signature sequencing. Each of these methods has...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Kidney Kidney development Kidney disease Gene expression...

... and gremlin (bone morphogenetic protein 2), have been identified, and their expression has been correlated with the tissue changes seen in diabetic nephropathy in the adult population. However, there are very few studies reported in the literature that describe the gene expression in the diabetic state during...

...Christiane van den Branden; Bart Ceyssens; Dirk De Craemer; Pieter De Bleser; Karine Hellemans; Albert Geerts; Dierik Verbeelen Reactive oxygen intermediates play a role in chronic renal injury and glomerulosclerosis. We investigate changes in renal cortex antioxidant enzyme gene expression...

... expression Hypoxia is known to be a potent regulator of gene expression [ 8, 9 ], increasing expression of genes encoding a variety of hormones (most notably, erythropoietin) [ 10, 11 ]; growth factors such as vascular endothelial cell growth factor (VEGF) [ 12, 13 ], platelet-derived growth...

...Anni Haltia; Marja-Liisa Solin; Pauliina Luimula; Matthias Kretzler; Harry Holthöfer Background: Differential display RT-PCR (DDRT-PCR) is a new powerful technique for identification and characterization of altered gene expression in eukaryotic cells and tissues. We studied here changes in kidney...