...Kieron L. Donovan; Nicholas Topley Defense against the susceptibility and damaging effects of urinary tract infection is complex and vital, as injury can lead to progressive renal injury and chronic renal failure. Recently the defensins, a family of small cationic antimicrobial peptides found...

...Martin Nitschke; Sandra Wiehl; Patrick C. Baer; Burkhard Kreft Renal tubular epithelial cells (RTC) form a barrier between the host and ascending microbes in upper urinary tract infection. Previous studies have shown the ability of the kidney to produce defensins – antimicrobial peptides that play...