...: Immunohistochemical analyses showed that the expression of Hic-5 was increased in mesangial cells (MCs) in human mesangial proliferative GN. Hic-5 expression was significantly correlated not only with the levels of α-smooth muscle actin (α-SMA) and TGF-β 1 , the accumulation of extracellular matrix, and the number...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2010 Glomerular epithelial cell Interstitial injury α-Smooth muscle actin Acute kidney injury SM22α Transgelin 5/6...

..., increased glomerular expression of desmin, glomerular and interstitial expression of α-smooth muscle actin and an increased number of ED-1-positive cells in glomeruli. An inverse correlation exists between catalase activity and glomerular α-smooth muscle actin expression and between glutathione peroxidase...

... their role in one of the commonest forms of nephrotic syndrome in adults, namely membranous nephropathy. We have studied 21 patients with biopsy proven idiopathic membranous nephropathy who were treated with glucocorticoids, attempting to define the role of myofibroblasts (α-smooth muscle actin-positive...