...Zhenhuang Zhuang; Yimin Zhao; Zimin Song; Wenxiu Wang; Ninghao Huang; Xue Dong; Wendi Xiao; Yueying Li; Jinzhu Jia; Zhonghua Liu; Lu Qi; Tao Huang Introduction: Time spent on screen-based sedentary activities is significantly associated with dementia risk, however, whether the associations vary...

...Xiaolu Xie; Liqiu Kou; Xiu Chen; Ping Yuan; Jun Li; Yaling Li Background: At present, the effect of aspirin in preventing dementia or mild cognitive impairment (MCI) is controversial. Clarifying their association is of interest for subsequent relevant clinical trials. Methods: Four databases...

.... Results: 1,049 patients were included (mean age ± SD: 76.3 ± 15.2 years old, 54% women). Case fatality rates at 5 years were 38.1% in patients without cognitive impairment, 65.9% in patients with prior mild cognitive impairment (MCI, n = 132, 12.6%), and 86.6% in patients with dementia ( n = 164, 15.6...

...Zeyu Zhu; Zhilin Zheng; Chen Zhou; Lanxiao Cao; Guohua Zhao Introduction: China has the largest population of people with dementia in the world and is estimated to have approximately a quarter of the entire population with dementia worldwide, bringing a heavy burden on the public and healthcare...

.... 2023 Huntington’s disease Chorea Dementia Depression Neurodegenerative diseases Chile Latin America Neuroepidemiology Genetics Huntington’s disease (HD) is a hereditary, autosomal dominant, neurodegenerative, and progressive disease leading to bedridden and death. Clinically, HD...

...Haomiao Jin; Eileen Crimmins; Kenneth M. Langa; A.B. Dey; Jinkook Lee Introduction: Accurate estimation of dementia prevalence is essential for making effective public and social care policy to support individuals and families suffering from the disease. The purpose of this paper is to estimate...

...Silvan Licher; Frank J. Wolters; Jelena Pavlović; Maryam Kavousi; Maarten J.G. Leening; M. Kamran Ikram; M. Arfan Ikram Introduction: Dementia prevention trials have so far shown little benefit of multidomain interventions against cognitive decline. Recruitment strategies in these trials often...

... disease Biomarkers Dementia Epidemiology Parkinson’s disease Population-based studies Public health Descriptive epidemiology is the basis of epidemiological research focusing on measuring disease occurrence (incidence and prevalence) and risk factor distribution. In this context...

...Vladimir Hachinski; Abolfazl Avan Background: During the past 40 years, dementia prevention approaches have ranged from searching for a drug to prevent progression to Alzheimer’s disease to preventing dementia through multidomain lifestyle interventions. Current Approaches: The search for a silver...

...Dongqing Gu; Shan Ou; Guodong Liu Introduction: Previous studies have investigated the potential role of traumatic brain injury (TBI) in subsequent development of dementia and Alzheimer’s disease (AD) but reported inconsistent results. We aimed to determine the association between TBI...

...GBD 2019 Dementia Collaborators Background: In light of the increasing trend in the global number of individuals affected by dementia and the lack of any available disease-modifying therapies, it is necessary to fully understand and quantify the global burden of dementia. This work aimed...

... and anticoagulants. Higher levels of circulating coagulants have been associated with higher risk of cerebral infarctions and dementia. In contrast, higher levels of circulating protein C, an endogenous anticoagulant, have been associated with lower risk of cerebral infarctions, and the association between protein C...

... factor for various noncommunicable diseases (NCDs) and is emerging as a risk factor for dementia. To begin to understand the full impact of PM 2.5 , we review the longitudinal epidemiological evidence linking PM 2.5 to both dementia and to other leading NCDs and highlight the evidence gaps. Our objective...

...Joshua R. Ehrlich; Tochukwu Ndukwe; Sandy Chien; Jinkook Lee Introduction: Due to population aging, India is poised to experience a large increase in the burden of both dementia and vision impairment (VI). Prior studies from other settings suggest that VI may be a modifiable risk factor...

...Melinda C. Power; Kan Z. Gianattasio; Adam Ciarleglio Introduction: Formal dementia ascertainment with research criteria is resource-intensive, prompting the growing use of alternative approaches. Our objective was to illustrate the potential bias and implications for study conclusions introduced...

...Chih-Ho Chou; I-Jung Feng; Yi-Chen Chen; Jiann-Hwa Chen; Hung-Jung Lin; Jhi-Joung Wang; Chien-Chin Hsu; Chien-Cheng Huang Background: A hyperglycemic crisis episode (HCE) signifies poor control of diabetes and may increase the risk of dementia via microvascular and macrovascular injuries...

...Tahmina Nasrin Poly; Md. Mohaimenul Islam; Bruno Andreas Walther; Hsuan-Chia Yang; Chieh-Chen Wu; Ming-Chin Lin; Yu-Chuan Li Background and Aims: The impact of statin on dementia risk reduction has been a subject of debate over the last decade, but the evidence remains inconclusive. Therefore, we...

... are limited. Summary: A review of published literature describing geographic distribution of DM and associated dementia in South Asian region, particularly India, was conducted with the purpose of assessing the feasibility and challenges associated with the Yoga-based risk reduction. PubMed and Google Scholar...

.... Stephan; Annalena Venneri; Fiona E. Matthews In recent years, a rapidly increasing collection of investigative methods in addition to changes in diagnostic criteria for dementia have followed “high-tech” trends in medicine, with the aim to better define the dementia syndrome and its biological substrates...

... with the inability to smell a certain odor. Objective: To verify the hypothesis that at least one specific odor is associated with incident cognitive decline among older adults. Methods: In the Shanghai Aging Study, a sub-cohort of 948 dementia-free participants who had baseline OI measurements were prospectively...