...Nabila Hamdi; Omnia Ocab; Radwa Soliman; Albert Ludolph; Wagida Anwar; Giancarlo Logroscino; Nagia Fahmy Background: There is a growing body of evidence indicating that the worldwide distribution of amyotrophic lateral sclerosis (ALS) is far from uniform. This is evident through variations...

...Mirka Hanhisuanto; Eino Solje; Manu Jokela; Jussi O.T. Sipilä Introduction: The incidence of amyotrophic lateral sclerosis (ALS) worldwide is approximately 1–2.6/1,000,000 and prevalence is 5–6/100,000. ALS has been suggested to be relatively common in Finland, but epidemiological information...

... amyotrophic lateral sclerosis (ALS). Materials and Methods: We conducted a population-based case-control study of U.S. Medicare enrollees from 2006 to 2013. The final sample included 3,714 incident ALS cases and 18,570 controls (matched on age, sex, enrollment length, and county). Information was collected...

... Kleveland; Helene Ballo Kvernmo; Unn Ljøstad; Angelina Maniaol; Åse Hagen Morsund; Ola Nakken; Camilla Novy; Tiina Rekand; Katrin Schlüter; Stephan Schüler; Kristian Tveten; Ole-Bjørn Tysnes; Trygve Holmøy; Helle Høyer Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease...

...Lorene M. Nelson; Barbara Topol; Wendy Kaye; Jaime Raymond; D. Kevin Horton; Paul Mehta; Todd Wagner Introduction: The Centers for Disease Control and Prevention (CDC) National Amyotrophic Lateral Sclerosis (ALS) Registry is the first national registry for a chronic neurologic disease in the USA...

...Carolyn A. Brown; Cathy Lally; Varant Kupelian; W. Dana Flanders Introduction: Amyotrophic lateral sclerosis (ALS) is a rare neurological disorder characterized by progressive deterioration of motor neurons. Assessment of the size/geographic distribution of the ALS population, including ALS...

...Jaime Raymond; Paul Mehta; Ted Larson; Erik P. Pioro; D. Kevin Horton Background: Amyotrophic lateral sclerosis (ALS) is a neurological disease of largely unknown etiology with no cure. The National ALS Registry is a voluntary online system that collects demographic and reproductive history...

...Chris Miller; Stephen Apple; Jeremy S. Paige; Tara Grabowsky; Oodaye Shukla; Wendy Agnese; Charlotte Merrill Background: Various methodologies have been reported to assess the real-world epidemiology of amyotrophic lateral sclerosis (ALS) in the United States. The aim of this study was to estimate...

.... Bradley Introduction: Amyotrophic lateral sclerosis (ALS) is a fatal, neuromuscular disease with no cure. ALS incidence rates have not been assessed specifically in Ohio, yet the state contains both metropolitan and rural areas with a variety of environmental factors that could contribute to disease...

...Guodong Liu; Shan Ou; Huijie Cui; Xuan Li; Zhiyong Yin; Dongqing Gu; Zhengguo Wang Background: Prior studies have suggested that head injury might be a potential risk factor of amyotrophic lateral sclerosis (ALS). However, the association has not been well established. We aimed to provide...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Epidemiology Methodology Low- and middle-income countries Population-based study Framework Epilepsy Dementia Amyotrophic lateral sclerosis Neurological...

...Carlos H. Zapata-Zapata; Edwing Franco Dáger; Daniel C. Aguirre-Acevedo; Mamede de Carvalho; Juan Solano-Atehortúa Introduction: The prevalence and incidence of amyotrophic lateral sclerosis (ALS) is not fully established, and this varies depending on the studied population. Objective: To estimate...

...Bebiana Conde; João Carlos Winck; Luís Filipe Azevedo Background: Amyotrophic lateral sclerosis (ALS) is a rare and progressive neurodegenerative disease involving the upper and lower motor neurons. It is also the most common and the one with the worst prognosis among the motor neuron diseases (MND...

...Giancarlo Logroscino; Marco Piccininni Amyotrophic lateral sclerosis (ALS) epidemiology has rapidly developed in the last 30 years alongside the evolving changes in concepts in the field of clinical ALS and also due to the recent proposals of new classification system for motor neuron diseases...

... likely varies depending on the disease under study. Methods: We used 3 case-finding sources (Medicare, Medicaid, and Veterans Administration data) to estimate the prevalence of amyotrophic lateral sclerosis (ALS) in the United States for 2002–2004, and applied the capture-recapture methodology...

...Theodore C. Larson; Wendy Kaye; Paul Mehta; D. Kevin Horton Background: The International Classification of Disease, 10th Revision (ICD-10) did not include a code specific for Amyotrophic lateral sclerosis (ALS) until 2017. Instead, code G12.2 included both ALS and other motor neuron diseases (MND...

...Mònica Povedano; Marc Saez; Juan-Antonio Martínez-Matos; Maria Antònia Barceló Background: It is believed that an interaction between genetic and non-genetic factors may be involved in the development of amyotrophic lateral sclerosis (ALS). With the exception of exposure to agricultural chemicals...

...Shenghan Zhou; Silin Qian; Xiaohan Li; Liping Zheng; Wenbing Chang; Liping Wang Background: To assess the total, gender-related and ageing process-related incidence rates of amyotrophic lateral sclerosis (ALS) in Beijing, China. Determine whether the decreased male to female ratio among...

...Meira Dandaba; Philippe Couratier; Anaïs Labrunie; Marie Nicol; Bello Hamidou; Marie Raymondeau; Giancarlo Logroscino; Pierre Marie Preux; Benoît Marin; FRALIM Consortium Background: Amyotrophic Lateral Sclerosis (ALS) is an age-related neurodegenerative disease with unclear characteristics...

...Christiana A. Demetriou; Petros M. Hadjivasiliou; Kleopas A. Kleopa; Yiolanda P. Christou; Eleni Leonidou; Theodoros Kyriakides; Eleni Zamba-Papanicolaou Introduction: Amyotrophic lateral sclerosis (ALS) is a rare, rapidly progressive neurodegenerative disease. Despite wide variability...