...Xiang Qi; Zheng Zhu; Katherine Wang; Yaguang Zheng; An Li; Bei Wu Introduction: This study examines the associations of gum treatment with cognitive decline and dementia risk among older adults with periodontal symptoms in the USA. Methods: A cohort of 866 adults aged ≥50 with periodontal symptoms...

...Yannick Béjot Background: The ongoing aging population in high-income countries is responsible for a dramatic rise in the number of elderly stroke patients in whom many questions remain regarding the use of acute revascularization therapy. This review aimed to compare stroke patients from...

... the prevalence of dementia in India using a semi-supervised machine learning approach based on a large nationally representative sample. Methods: The sample of this study is adults 60 years or older in the wave 1 (2017–2019) of the Longitudinal Aging Study in India (LASI). A subsample in LASI received extensive...

... and aging is essential for delaying morbidity and maximizing independence in aging populations as life expectancies increase. Loss of cognitive function is a feared age-associated condition and growing public health concern. Alzheimer’s disease (AD), the most common cause of dementia, has no curative...

...Zoe Arvanitakis; Ana W. Capuano; Robin Brey; Debra A. Fleischman; Konstantinos Arfanakis; Aron S. Buchman; Julie A. Schneider; Steven R. Levine; David A. Bennett Background: Few data are available on associations of antiphospholipid (aPL) antibodies with cognitive and motor decline in aging...

...Elan D. Louis Background: With an aging population, it behooves physicians and scientists to gain an understanding of the intersections between aging and human disease. Here, the author reviews the intersections between age, aging, and essential tremor (ET), particularly as these relate to disease...

...Ettore Beghi; Giorgia Giussani Background: Epilepsy is a chronic disorder affecting all ages but with a peak in the elderly. The association of epilepsy with age can be explained by the predominance of brain diseases with epileptogenic potential (mostly stroke and dementia) and by the effects...

.... Methods: The World Health Organization Study on Global AGEing and Adult Health data was used to examine cognition among 6,244 community-residing adults age 50+ in 6 states in India. Residential status was categorized as urban, rural, urban-to-urban, rural-to-urban, rural-to-rural, and urban-to-rural...

...V. Eloesa McSorley; Jayant Pinto; L. Philip Schumm; Kristen Wroblewski; David Kern; Martha McClintock; Diane S. Lauderdale Background: Sleep and olfaction are both critical physiological processes that tend to worsen with age. Decline in olfaction can be an early indicator of neurodegenerative...

... elderly (aged ≥85 years) with a first-ever ischemic stroke in the National Acute Stroke Israeli Survey (NASIS) registry. Methods: The NASIS registry is a nationwide prospective hospital-based study performed triennially (2004, 2007, 2010). Patients with ischemic stroke aged ≥85 years were compared...

...: During up to 16 years of annual follow-up, 339 of 607 persons (56%) developed MCI. In a proportional hazards model adjusted for age, sex and education, the presence of the APOE ε 4 allele was associated with a 1.4-fold increased risk of incident MCI (hazard ratio: 1.36; 95% CI: 1.04, 1.78). Further...

... the impact of exercise on mortality and 5-year changes in cognition. Methods: In the Canadian Study of Health and Aging (n = 8,403, 60.7% women), cognitive states were defined as errors in the Modified Mini-Mental State Examination. Improvement and declines were modeled using a 4-parameter truncated Poisson...

... ambulatory older persons without dementia who underwent annual clinical evaluations to examine change in the rate of mobility over time. Results: In a linear mixed-effect model adjusted for age, sex, and education, mobility declined about 0.12 unit/year, and higher levels of respiratory muscle strength were...

... sample. Methods: The Aging, Demographics, and Memory Study sample was composed of 856 individuals aged 71 years and older from the nationally representative Health and Retirement Study (HRS) who were evaluated for dementia using a comprehensive in-home assessment. An expert consensus panel used...

.... The main objectives of the study were to assess the prevalence, types and severity of dementia among elderly people (≥55 years old) in an urban area on the Caribbean coast of Venezuela, and to determine the gender and age distribution of affected people. Methods: The population-based Maracaibo Aging Study...

... older persons without dementia at baseline and risk of AD. In a proportional hazards model adjusted for age, sex and education, each 1-lb decrease in grip strength at baseline was associated with about a 1.5% increase in the risk of AD (HR, 0.986; 95% CI, 0.973–0.998). These results persisted even after...

...-dwelling African American and Caucasian elders. Methods: 433 African Americans and 477 Caucasians over the age of 65 were recruited. Executive function was assessed using CLOX1, a command-directed clock drawing task. Posterior cortical impairment was assessed using CLOX2, a clock copy task. CLOX scores...

... The relationship between age-related white matter changes and cognitive performance in independent elderly people is still not clear. The Leukoaraiosis and Disability in the Elderly study (LADIS) involves 11 European centers. It aims to assess the role of the age-related white matter changes as an independent...

... the design and methods of the Aging, Demographics, and Memory Study (ADAMS), a new national study that will provide data on the antecedents, prevalence, outcomes, and costs of dementia and ‘cognitive impairment, not demented’ (CIND) using a unique study design based on the nationally representative Health...

... Age-related white matter changes (ARWMC) on brain MRI have been associated with cognitive, motor, mood and urinary disturbances. These factors are known to contribute to disability in elderly people, but the impact of ARWMC and of their progression on the transition to disability is not determined...