Traumatic brain injury (TBI) is a significant public-health concern. To understand the extent of TBI, it is important to assess the prevalence of TBI in the general population. However, the prevalence of TBI in the general population can be difficult to measure because of differing definitions of TBI, differing TBI severity levels, and underreporting of sport-related TBI. Additionally, prevalence reports vary from study to study. In this present study, we used meta-analytic methods to estimate the prevalence of TBI in the adult general population. Across 15 studies, all originating from developed countries, which included 25,134 adults, 12% had a history of TBI. Men had more than twice the odds of having had a TBI than did women, suggesting that male gender is a risk factor for TBI. The adverse behavioral, cognitive and psychiatric effects associated with TBI coupled with the high prevalence of TBI identified in this study indicate that TBI is a considerable public and personal-health problem.

Keywords:
Prevalence, General population prevalence, Traumatic brain injury
1.
Consensus conference: Rehabilitation of persons with traumatic brain injury. NIH consensus development panel on rehabilitation of persons with traumatic brain injury. JAMA 1999;282:974–983.
2.
Faul M, Xu L, Wald MM, Coronado VG: Traumatic brain injury in the United States: emergency department visits, hospitalizations and deaths 2002–2006. Atlanta, Centers for Disease Control and Prevention, National Center for Injury Prevention and Control, 2010.
3.
Roebuck-Spencer T, Sherer M: Moderate and severe traumatic brain injury; in Morgan JE, Ricker JH (eds): Textbook of Clinical Neuropsychology. New York, Taylor & Francis, 2008, pp 411–429.
4.
Cassidy JD, Carroll LJ, Peloso PM, Borg J, von Holst H, Holm L, Kraus J, Coronado VG: Incidence, risk factors and prevention of mild traumatic brain injury: results of the WHO Collaborating Centre task force on mild traumatic brain injury. J Rehabil Med 2004;43(suppl)28–60.
5.
Corrigan JD, Selassie AW, Orman JA: The epidemiology of traumatic brain injury. J Head Trauma Rehabil 2010;25:72–80.
6.
Orman JAL, Kraus JF, Zaloshnja E, Miller T: Epidemiology; in Silver JM, McAllister TW, Yudofsky SC (eds): Textbook of Traumatic Brain Injury. Arlington, American Psychiatric Publishing, 2011, pp 3–22.
7.
Turkstra L, Jones D, Toler HL: Brain injury and violent crime. Brain Inj 2003;17:39–47.
8.
Butterworth P, Anstey K, Jorm AF, Rodgers B: A community survey demonstrated cohort differences in the lifetime prevalence of self-reported head injury. J Clin Epidemiol 2004;57:742–748.
9.
Farrer TJ, Hedges DW: Prevalence of traumatic brain injury in incarcerated groups compared to the general population: a meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry 2011;35:390–394.
10.
Farrer TJ, Frost RB, Hedges DW: Prevalence of traumatic brain injury in juvenile offenders: a meta-analysis. Child Neuropsychol 2012, E-pub ahead of print.
11.
Borenstein M, Hedges LV, Higgins JPT, Rothstein HR: Introduction to Meta-Analysis. Chichester, Wiley & Sons, 2009.
12.
Zaloshnja E, Miller T, Langlois JA, Selassie AW: Prevalence of long-term disability from traumatic brain injury in the civilian population of the United States, 2005. J Head Trauma Rehabil 2008;23:394–400.
13.
Selassie AW, Zaloshnja E, Langlois JA, Miller T, Jones P, Steiner C: Incidence of long-term disability following traumatic brain injury hospitalization, United States, 2003. J Head Trauma Rehabil 2008;23:123–131.
14.
Larson MJ, Fair JE, Farrer TJ, Perlstein WM: Predictors of performance monitoring abilities following traumatic brain injury: the influence of negative affect and cognitive sequelae. Int J Psychophysiol 2011;82:61–68.
15.
Rao V, Lyketsos C: Neuropsychiatric sequelae of traumatic brain injury. Psychosomatics 2000;41:95–103.
16.
Rogers JM, Read CA: Psychiatric comorbidity following traumatic brain injury. Brain Inj 2007;21:1321–1333.
17.
Van Reekum R, Cohen T, Wong J: Can traumatic brain injury cause psychiatric disorders? J Neuropsychiatry Clin Neurosci 2000;12:316–327.
18.
Mateo MA, Glod CA, Hennen J, Price BH, Merrill N: Mild traumatic brain injury in psychiatric inpatients. J Neurosci Nurs 2005;37:28–33.
19.
McGuire LM, Burright RG, Williams R, Donovick PJ: Prevalence of traumatic brain injury in psychiatric and non-psychiatric subjects. Brain Inj 1998;12:207–214.
20.
Guskiewicz KM, McCrea M, Marshall SW, Cantu RC, Randolph C, Barr W, Onate JA, Kelly JP: Cumulative effects associated with recurrent concussion in collegiate football players: The NCAA Concussion Study. JAMA 2003;290:2549–2555.
21.
Millis SR, Rosenthal M, Novack TA, Sherer M, Nick TG, Kreutzer JS, High WM Jr, Ricker JH: Long-term neuropsychological outcome after traumatic brain injury. J Head Trauma Rehabil 2001;16:343–355.
22.
Langlois JA, Rutland-Brown W, Wald MM: The epidemiology and impact of traumatic brain injury: a brief overview. J Head Trauma Rehabil 2006;21:375–378.
23.
Moser RS, Iverson GL, Echemendia RJ, Lovell MR, Schatz P, Webbe FM, Ruff RM, Barth JT: Neuropsychological evaluation in the diagnosis and management of sports-related concussion. Arch Clin Neuropsychol 2007;22:909–916.
24.
Injury prevention and control: traumatic brain injury. Centers for Disease Control and Prevention, 2012. http://www.cdc.gov/traumaticbraininjury.
25.
Bigler ED: Neuropsychology and clinical neuroscience of persistent post-concussive syndrome. J Int Neuropsychol Soc 2008;14:1–22.
26.
Boswell JE, McErlean M, Verdile VP: Prevalence of traumatic brain injury in an ED population. Am J Emerg Med 2002;20:177–180.
27.
Demakis GJ, Rimland CA: Untreated mild traumatic brain injury in a young adult population. Arch Clin Neuropsychol 2010;25:191–196.
28.
Holmes CB, Buzzanga VL: Head-injury prevalence among community college students. Percept Mot Skills 1991;73:497–498.
29.
McKinlay A, Grace RC, Horwood LJ, Fergusson DM, Ridder EM, MacFarlane MR: Prevalence of traumatic brain injury among children, adolescents and young adults: prospective evidence from a birth cohort. Brain Inj 2008;22:175–181.
30.
Perkes I, Schofield PW, Butler T, Hollis SJ: Traumatic brain injury rates and sequelae: a comparison of prisoners with a matched community sample in Australia. Brain Inj 2011;25:131–141.
31.
Segalowitz SJ, Lawson S: Subtle symptoms associated with self-reported mild head injury. J Learn Disabil 1995;28:309–319.
32.
Silver JM, Kramer R, Greenwald S, Weissman M: The association between head injuries and psychiatric disorders: findings from the New Haven NIMH epidemiologic catchment area study. Brain Inj 2001;15:935–945.
33.
Templer DI, Kasiraj J, Trent NH, Trent A, Hughey B, Keller WJ, Orling RA, Thomas-Dobson S: Exploration of head injury without medical attention. Percept Mot Skills 1992;75:195–202.
34.
Ryan LM, O’Jile JR, Gouvier WD, Parks-Levy J, Betz B: Head injury in a college population: analysis of epidemiological factors. Appl Neuropsychol 1996;3:49–54.
35.
Crovitz HF, Horn RW, Daniel WF: Inter-relationships among retrograde amnesia, post-traumatic amnesia, and time since head injury: a retrospective study. Cortex 1983;19:407–412.
36.
Crovitz HF, Diaco DS, Apter A: Consistency in recalling features of former head injuries: retrospective questionnaire versus interview retest. Cortex 1992;28:509–512.
37.
Crovitz HF, Daniel WF: Length of retrograde amnesia after head injury: a revised formula. Cortex 1987;23:695–698.
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2012
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