... in the pathogenesis of chronic kidney disease (CKD) and diabetes mellitus. The aim of our study was to assess the proinflammatory state of nondialysis CKD patients by evaluating the membrane expression of TLR2 and TLR4 and the intracellular IL-1β and IL-6 production in response to the ligand Pam3Cys-Ser-(Lys)4...

... the predictors of hyperkalemia risk following hypertension control using aldosterone blockade in the presence or absence of chronic kidney disease (CKD). Methods: A total of 6,575 patients with hypertension treated between January 1, 2000, and November 30, 2012, were evaluated for the safety of an aldosterone...

... disease Uremic compounds Renal dysfunction Inadequate removal of a large number of potentially toxic organic metabolites from the vascular bed into the urine in the course of acute kidney injury (AKI) and chronic kidney disease (CKD) is associated with various clinical symptoms which are often...

...Seon Ha Baek; Sejoong Kim; Dong Ki Kim; Jung Hwan Park; Sung Joon Shin; Sang Ho Lee; Bum Soon Choi; Ho Jun Chin; Suhnggwon Kim; Chun Soo Lim Background/Aims: An acid-base imbalance precedes renal disease progression in patients with chronic kidney disease (CKD). Little is known about the effects...

.... One particular challenge is an increase in chronic kidney disease, the prevalence of which is higher in older people. This article reviews the key links between kidney function, age, health and illness, and discusses the implications of the ageing population for the care of people with chronic kidney...

... components [all-cause mortality, myocardial infarction (MI) or cerebrovascular events (CVE)], in multiple post hoc analyses of 9 prospective RCTs (3,405 chronic kidney disease patients). Mean Hb levels over time and deviation from target were analysed using a Cox regression model. Time-adjusted average Hb...

... kidney disease Inflammation Sodium Chronic kidney disease (CKD) is known to affect the ability of the kidneys to regulate water homeostasis [ 1 ]. During the course of CKD, both the maximum dilution and concentration of the urine gradually decline with the capacity to dilute typically being...

... to in the content or advertisements. Endotoxin Chronic kidney disease Haemodialysis Frequent dialysis Quotidian dialysis Nocturnal dialysis Inflammation Ischaemia Circulatory stress Dialysis patients display hugely elevated rates of cardiac mortality [ 1 ], driven by pathophysiological...

...Shabnam Salimi; Nawi Ng; Stephen L. Seliger; Afshin Parsa Background: Leukocytosis is a powerful predictor of incident chronic kidney disease (CKD) and related outcomes. However, the association between periodontitis measures and increased leukocytosis in the context of CKD has not been well...

...Isabel Rodriguez Villarreal; Olimpia Ortega; Julie Hinostroza; Gabriela Cobo; Paloma Gallar; Carmen Mon; Juan Carlos Herrero; Milagros Ortiz; Cristina Di Giogia; Aniana Oliet; Ana Vigil In patients older than 75 years with advanced chronic kidney disease (CKD), the decision between treatment...

...Sharlene A. Greenwood; Pelagia Koufaki; Robert Rush; Iain C. Macdougall; Thomas H. Mercer; On behalf of the British Renal Society Rehabilitation Network Background: Patients with chronic kidney disease (CKD) have elevated cardiovascular disease (CVD) risk. Physical activity (PA) is a strong...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Functional status Mortality Chronic kidney disease Progression Chronic kidney disease (CKD) associates with excess morbidity and mortality, with risk for death increasing...

... to in the content or advertisements. Chronic kidney disease Bleeding Desmopressin Renal biopsy Renal failure Patients with renal failure are known to have an increased tendency for bleeding. The reason for this is likely due to various comorbidities, medications, etc. However, it is felt...

...Fabiana B. Nerbass; Roberto Pecoits-Filho; Natasha J. McIntyre; Christopher W. McIntyre; Maarten W. Taal Background/Aims: High sodium intake is associated with adverse cardiovascular and renal outcomes in people with chronic kidney disease (CKD), and simple methods to facilitate assessment...

.... Cardiotonic steroids Chronic kidney disease End-stage renal disease Sodium potassium pump Ouabain Marinobufagenin Bufalin Telocinobufagin Digoxin There is a complex relationship between the kidneys and the heart, with the activity of kidneys strongly influencing the activity of the heart...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute kidney injury Chronic kidney disease...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute kidney injury Chronic kidney disease...

...Michael Heung; Lakhmir S. Chawla This review examines the evidence linking acute kidney injury (AKI) with the risk of subsequently developing chronic kidney disease (CKD). The discussion focuses on subjects that recover from an episode of AKI, most of whom do not receive follow-up nephrology care...

... clinical outcomes, including the development of chronic kidney disease (CKD) and end-stage renal disease (ESRD) [ 2,3,4 ]. Although, until recently, it was thought that survivors from an AKI episode frequently recover kidney function, cumulative observational data over the past decade have confirmed...

... of both the initial insult and the subsequent repair. Limited but recent experimental data have revealed that the intestinal microbiota significantly affects outcomes in AKI. Additional evidence shows significant changes in the intestinal microbiota in chronic kidney disease patients and in experimental...