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Keywords: acute kidney injury
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Journal Articles
Journal Articles
Subject Area:
Nephrology
Nephron Clinical Practice (2015) 128 (3-4): 303–311.
Published Online: 19 December 2014
... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute kidney injury Chronic kidney...
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Subject Area:
Nephrology
Nephron Clinical Practice (2014) 127 (1-4): 10–14.
Published Online: 24 September 2014
...Isaah S. Vincent; Mark D. Okusa Acute kidney injury (AKI) contributes to progressive kidney disease. Although significant advances have been made in the understanding of mechanisms of AKI, less is known about the biological basis that links the initial injury to progressive interstitial fibrosis...
Journal Articles
Subject Area:
Nephrology
Nephron Clinical Practice (2014) 127 (1-4): 89–93.
Published Online: 24 September 2014
...Frederic T. Billings IV; Andrew D. Shaw The development and use of consensus criteria for acute kidney injury (AKI) diagnosis and the inclusion of recently identified markers of renal parenchymal damage as endpoints in clinical trials have improved the ability of physicians to compare the incidence...
Journal Articles
Subject Area:
Nephrology
Nephron Clinical Practice (2014) 127 (1-4): 25–29.
Published Online: 24 September 2014
...Mélanie Godin; Etienne Macedo; Ravindra L. Mehta Acute kidney injury (AKI) is associated with increased mortality, prolonged hospitalization, and renal replacement therapy. Until recently, it was believed that the vast majority of patients recover from AKI without subsequent consequences. It is now...
Journal Articles
Subject Area:
Nephrology
Nephron Clinical Practice (2014) 127 (1-4): 176–179.
Published Online: 24 September 2014
...Prasad Devarajan; Patrick Murray Novel biomarkers are required to improve the timely detection of early acute kidney injury (AKI) and to improve the differential diagnosis, prognostic assessment, and management of AKI cases. It is anticipated that novel biomarkers of early structural AKI (‘acute...
Journal Articles
Subject Area:
Nephrology
Nephron Clinical Practice (2014) 127 (1-4): 30–34.
Published Online: 24 September 2014
...Michael Heung; Lakhmir S. Chawla This review examines the evidence linking acute kidney injury (AKI) with the risk of subsequently developing chronic kidney disease (CKD). The discussion focuses on subjects that recover from an episode of AKI, most of whom do not receive follow-up nephrology care...
Journal Articles
Subject Area:
Nephrology
Nephron Clinical Practice (2014) 127 (1-4): 101–105.
Published Online: 24 September 2014
...Zoltán H. Endre Establishing the prognosis for recovery has enormous clinical implications. The appropriate definition of renal recovery depends on the stage of acute kidney injury (AKI). As definitions of AKI have broadened to encompass small increases in serum creatinine, definitions of recovery...
Journal Articles
Subject Area:
Nephrology
Nephron Clinical Practice (2014) 127 (1-4): 180–184.
Published Online: 24 September 2014
... cutoffs for biomarker concentrations. These limitations are increased by comparison with serum creatinine to define acute kidney injury. The critical problem affecting biomarker performance is patient heterogeneity involving the cause, context (including comorbidity and baseline renal function...
Journal Articles
Journal Articles
Journal Articles
Subject Area:
Nephrology
Nephron Clinical Practice (2014) 127 (1-4): 42–45.
Published Online: 24 September 2014
...Mei Tran; Samir M. Parikh Mitochondrial dysfunction within the tubular epithelium has been implicated in the pathogenesis of acute kidney injury. Inflammatory, ischemic, or toxic insults dysregulate mitochondrial dynamics, resulting in mitochondrial swelling, fission, and apoptosis. The coordinated...
Journal Articles
Subject Area:
Nephrology
Nephron Clinical Practice (2014) 127 (1-4): 56–60.
Published Online: 24 September 2014
...Liyu He; Man J. Livingston; Zheng Dong Acute kidney injury (AKI) is a major kidney disease associated with a poor clinical outcome both in the short and long term. Autophagy is a cellular stress response that plays important roles in the pathogenesis of various diseases. Autophagy is induced...
Journal Articles
Journal Articles
Journal Articles
Subject Area:
Nephrology
Nephron Clinical Practice (2014) 127 (1-4): 75–80.
Published Online: 24 September 2014
... of time point and dose of MSC administered, time point of sCr measurement, route of MSC delivery, type of kidney injury and animal used (mice vs. rats). Subanalyses showed that the reduction in sCr in acute kidney injury (AKI) models was highest in ischemia-reperfusion injury (mean, 43 µmol/l reduction...