... oxidative stress levels and antioxidant potential and to analyze the relationship with serum uric acid (UA) levels. Methods and Results: Oxidative stress levels (derivatives of reactive oxygen metabolites, d-ROMs) and antioxidant potential (biological antioxidant potential, BAP) were measured in individuals...

... of CV disease in patients with CKD and that there are several ‘CKD-specific' ‘non-traditional' risk factors that explain the unacceptably high CV morbidity and mortality in this cohort [ 5,6 ]. Arterial injury Endothelial dysfunction Inflammation Oxidative stress Chronic kidney disease...

... hypertrophy by decreasing oxidative stress and increasing the serum nitric oxide production in hemodialysis patients with SHPT. Nitrate is the primary final oxidation product of nitric oxide and circulates in levels up to 1,000-fold higher than that of nitrite; therefore, we measured the cumulative...

... nephropathy. Up to 25% of patients with MH-associated AKI do not recover baseline renal function. Our objective was to identify subjects at high risk for an adverse renal function. Methods: We examined macrophages, oxidative stress markers (NADPH-p22 and HO-1) and the hemoglobin scavenger receptor (CD163...

... IS and iron-dextran (ID) regarding iron release and induction of oxidative stress. Methods: Twenty hemodialysis patients were enrolled. Plasma iron and oxidative stress parameters were measured before and 10 min after intravenous (IV) injection of 100 mg IS and ID, respectively. Results: Intravascular iron...

...Shih-Ping Hsu; Chih-Kang Chiang; Shao-Yu Yang; Chiang-Ting Chien Background/Aims: To explore the efficacy of oral N-acetylcysteine (NAC) supplementation for anemia and oxidative stress in hemodialysis (HD) patients. Methods: Of the eligible patients (n = 325) in an outpatient HD unit, 49 received...

...R. Coppo; R. Camilla; A. Amore; L. Peruzzi IgA nephropathy (IgAN) is characterized by mesangial deposits of IgA1, likely due to accumulation of IgA immune complexes. The activation of intracellular signaling mostly results in oxidative stress, as detected in mesangial cells cultured with aberrantly...

...Bernardo Rodríguez-Iturbe; Guillermo García García There is compelling evidence that interstitial inflammation plays a central role in the loss of renal function in chronic renal disease. The combined effects of interstitial inflammation, oxidative stress and local angiotensin II activity result...

...Simeone Andrulli; Salvatore Di Filippo; Celestina Manzoni; Luca Stefanelli; Alessandro Floridi; Francesco Galli; Francesco Locatelli Background: Oxidative stress, a recently identified factor related to the response to erythropoiesis-stimulating agents (ESAs), is increased in hemodialysis patients...

...Juan F. Macías Núñez; Zoubiair Ghais; Jesus Bustamante; Jose M. Lopez-Novoa Background: Haemodialysis (HD) exacerbates oxidative stress (OS). The polymethyl-methacrylate (PMMA)-BK-F membrane ameliorates OS and inflammation markers compared to polyacrylonitrile (PAN/AN69) and cellulose membranes...

... of the present investigation was to evaluate the levels of plasma carbonyl formation, a sensitive marker of enhanced oxidative stress in predialysis, hemodialysis (HD) and peritoneal dialysis (PD) patients. Methods: Plasma samples from 20 apparently healthy control individuals and 127 CKD (stages 2, 3, 4, HD...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hemodialysis Electrolyzed water Oxidative stress Methylglyoxal Neutrophils Evidence suggests that enhanced oxidative stress plays a crucial role in poor outcomes...

...Kazunori Washio; Masahiro Inagaki; Mayumi Tsuji; Yuri Morio; Shinichiro Akiyama; Hiromichi Gotoh; Tomomi Gotoh; Yoshikazu Gotoh; Katsuji Oguchi Background/Aim: Oxidative stress is known to be enhanced in hemodialysis patients, and one of its useful markers is plasma copper/zinc superoxide dismutase...

...Michal Herman; Yaacov Ori; Avry Chagnac; Asher Korzets; Talia Weinstein; Tsipora Malachi; Uzi Gafter Background: Hemodialysis (HD) patients are subjected to increased oxidative stress. Oxidative stress causes DNA damage, which may be repaired by a DNA repair system. ‘Spontaneous DNA repair...

... therapy-insensitive association between homocysteinemia and plasma free thiol levels was found in ESRD patients. These results support a role for oxidative stress in ESRD-related hyperhomocysteinemia and suggest the plasma thiol redox status alteration as a possible pathogenic mechanism underlying...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Vitamin C Oxidative stress Hemodialysis Malondialdehyde Vitamin C (ascorbic acid, AA) has a variety of metabolic functions that are largely dependent on its potent...

... (TFPI) and oxidative stress (SOX). Methods: We assessed TF, TFPI and a marker of SOX, Cu/Zn superoxide dismutase (Cu/Zn SOD) in 16 diabetic CAPD patients (8 with EPO therapy), 39 non-diabetic CAPD patients (23 with EPO therapy) and 18 healthy controls. Results: Patients on CAPD showed a significant...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hemodialysis Oxidative stress Cholesteryl ester hydroperoxide Phosphatidylcholine hydroperoxide Apolipoprotein A-I Lecithin:cholesterol acyltransferase Hydroxyl radical Free...

...Aki Hirayama; Sohji Nagase The importance of analyzing the kinetics of reactive oxygen species or related substances in vivo is increasing. Electron paramagnetic resonance (EPR) is currently a powerful method for in vivo, non-invasive analysis of oxidative stress. We have applied EPR imaging...

... compared with the normal population. The definite mechanism responsible for the host defense alterations is not well understood. The aim of the study was to investigate intracellularly the relationship between cytokine synthesis and oxidative stress in peripheral blood lymphocytes in children with ESRD...