...Shih-Han S. Huang; Misha Eliasziw; J. David Spence; Guido Filler; William C. Vezina; David N. Churchill; Daniel C. Cattran; Bonnie Richardson; Andrew A. House Background: Isotopic glomerular filtration rate (iGFR) measurement is comparable to the inulin method. In this study, we compared urinary...

...Aashish Sharma; Marìa Jimena Mucino; Claudio Ronco Renal functional reserve (RFR) represents the capacity of the kidney to increase glomerular filtration rate (GFR) in response to certain physiological or pathological stimuli or conditions. Once baseline GFR is determined, RFR can be assessed...

... filtration rate Living kidney donors Time-dependent changes in CAC Due to organ shortage, live kidney donation is increasing worldwide [ 1 ]. Data on the long-term mortality and morbidity of living kidney donors are scarce [ 2 ]. Unilateral nephrectomy causes a mild or moderate glomerular...

...Cristian Pattaro; Peter Riegler; Gerald Stifter; Mirko Modenese; Cosetta Minelli; Peter P. Pramstaller Background/Aims: Several formulas for glomerular filtration rate (GFR) estimation, based on serum creatinine or cystatin C, have been proposed. We assessed the impact of some of these equations...

...Sverrir I. Gunnarsson; Runolfur Palsson; Gunnar Sigurdsson; Olafur S. Indridason Background: Differences in body composition may lead to imprecision in estimates of glomerular filtration rate (eGFR) derived from serum creatinine. Our aims were to examine the relationship between eGFR...

... the association of estimated glomerular filtration rate (eGFR) and urinary protein to creatinine (UPr/UCr) ratio with relevant patient, disease and laboratory indices. Results: The median age of patients was 28 years (44% males). The eGFR was >90 ml/min/1.73 m 2 in all patients, with a median value of 142.3 ml...

... controls over a period of 14 years. Methods: Renal function was measured 1 and then 14 years postpartum by para-aminohippurate and inulin clearances in 20 women with a history of severe preeclampsia and 8 parous controls. Results: The difference in glomerular filtration rate 1 year postpartum between women...

..., blacks with normal kidney function have lower urinary potassium excretion, but it is unclear if such differences have a bearing on race-associated outcomes in CKD. Methods: We studied predialysis mortality and slopes of estimated glomerular filtration rate, eGFR) associated with serum potassium in 1,227...

...Pierre Delanaye; Jean-Marie Krzesinski Indexation of glomerular filtration rate (GFR) by body surface area (BSA) is often done without raising any questions. In this article, we will shortly review the limitations of such indexation and illustrate potential errors in clinical practice due...

... tract and Pneumocystis jirovecii infections. The Sfx component appears to be nephrotoxic at high doses or doses inappropriately adjusted for glomerular filtration rate (GFR). The trimethoprim component, even at recommended doses, inhibits tubular creatinine secretion, leading to a rapid but ultimately...

... or conducted stratified analysis by age. It does appear that elderly patients with estimated glomerular filtration rate (eGFR) 45–59 ml/min/1.73 m 2 are at higher risk for AKI compared with their counterparts with eGFR >60 ml/min/1.73 m 2 . This is a similar relationship to that seen in younger patients...

...James Goya Heaf; Leif Spange Mortensen Introduction: Chronic kidney disease (CKD) is a progressive disease leading to loss of glomerular filtration rate (ΔGFR, measured in ml/min/1.73 m 2 /year). ΔGFR is usually assumed to be constant, but the hyperfiltration theory suggests that it accelerates...

...Timothy J. Ellam Current guidelines illogically recommend that a different approach is taken to the correction for creatinine generation rate when estimating glomerular filtration rate (GFR) and when interpreting urine albumin:creatinine ratio (ACR). Age, gender and race are routinely used...

... of inhibitors of the renin-angiotensin-aldosterone system. The routine measurement of the urinary protein/albumin:creatinine ratio (PCR/ACR) and estimated glomerular filtration rate (eGFR) gives rise to the opportunity to index proteinuria for renal function (i.e. a PCR:eGFR or ACR:eGFR ratio). Since both PCR...

...Joanna Q. Hudson; Darius L. Mason; Kim M. Huch Background/Aims: Methods for assessing glomerular filtration rate (GFR) are controversial in obese individuals. This study compared clinical estimates of GFR in African Americans (AA) with chronic kidney disease (CKD) overall and by body mass index...

...H.N. Lima; N.L. Cabral; A.R.R. Gonçalves; A. Hauser; R. Pecoits-Filho Background/Aims: In an attempt to find new predictors of stroke prognosis, we evaluated the association of albuminuria (AUr) and the estimated glomerular filtration rate (eGFR) with the recurrence of stroke and mortality. Methods...

...Simon de Lusignan; Charles Tomson; Kevin Harris; Jeremy van Vlymen; Hugh Gallagher Background/Aims: Cases of chronic kidney disease (CKD) are defined by the estimated glomerular filtration rate (eGFR), calculated using the Modified Diet in Renal Disease (MDRD) or, more recently, the CKD...

...Allon N. Friedman; Matthew Strother; Sara K. Quinney; Stephen Hall; Susan M. Perkins; Edward J. Brizendine; Margaret Inman; Gerardo Gomez; Zak Shihabi; Sharon Moe; Lang Li Background: Identifying methods to accurately measure the glomerular filtration rate (GFR) in obese individuals without kidney...

...Rafik Helou Background/Aims: Although the National Kidney Disease Education Program recommends use of the modification of diet in renal disease (MDRD) formula to estimate the glomerular filtration rate (GFR), most drug-dosing recommendations and clinical practices employ the Cockcroft-Gault (CG...

...A. Michael Peters; Hayley L.R. Snelling; Daphne M. Glass; Shirley Love; Nicholas J. Bird Background/Aims: To compare body surface area (BSA) with lean body mass (LBM) for scaling extracellular fluid volume (ECV) and glomerular filtration rate (GFR). Methods: Phase 1: Total body water (TBW), bromide...