...Cheng Xue; Bing Dai; Changlin Mei Background: The role of the mammalian target of rapamycin (mTOR) inhibition in the treatment of autosomal dominant polycystic kidney disease (ADPKD) remains unclear. This meta-analysis included all randomized controlled trials (RCTs) that used mTOR inhibitors...

...Ismail Kocyigit; Mahmut Ilker Yilmaz; Ozcan Orscelik; Murat Hayri Sipahioglu; Aydin Unal; Eray Eroglu; Nihat Kalay; Bulent Tokgoz; Jonas Axelsson; Oktay Oymak Background/Aims: Patients with autosomal dominant polycystic kidney disease (ADPKD) exhibit endothelial dysfunction (ED) despite normal...

...Ming-Yang Chang; Albert C.M. Ong Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease, accounting for up to 10% of patients on renal replacement therapy. There are presently no proven treatments for ADPKD and an effective disease-modifying drug would have...

... and also the rapid progress being made internationally in translating genetic knowledge for patient benefit in autosomal dominant polycystic kidney disease, the most common inherited kidney disease. 11 11 2010 © 2010 S. Karger AG, Basel 2010 Open Access License / Drug Dosage / Disclaimer...

...York Pei Autosomal dominant polycystic kidney disease (ADPKD) is the most common mendelian disorder of the kidney and accounts for ∼5% of end-stage renal disease in North America. It is characterized by focal development of renal cysts which increase in number and size with age. Mutations of PKD1...

...: Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease. It accounts for 5–10% of patients with end-stage renal disease (ESRD). The aim of this multicenter study was to investigate the demographic and clinical characteristics of patients with ADPKD. Methods: 1,139...

...Xiucai Jin; Shu Rong; Changlin Mei; Jiabin Chen; Chaoyang Ye; Xiaoyu Chen Objective: To study changes in myocardial wall texture in autosomal dominant polycystic kidney disease (ADPKD) patients by ultrasonic integrated backscatter (IBS) analysis. Methods: Hypertensive and normotensive ADPKD...

...Alfonso Ramunni; Paola Brescia; Domenico Quaranta; Maria Stella Bianco; Prudenza Ranieri; Ernesta Dolce; Pasquale Coratelli Background/Aims: An endothelial dysfunction has been described in autosomal dominant polycystic kidney disease (ADPKD) before the development of hypertension and renal...

... complication of autosomal dominant polycystic kidney disease. Such infections are classified into those affecting hepatic cysts and those affecting renal cysts. The purpose of this study was to compare the clinical course of infected hepatic cysts with that of infected renal cysts in patients with autosomal...

...Kikuo Nutahara; Eiji Higashihara; Shigeo Horie; Kouichi Kamura; Ken Tsuchiya; Toshio Mochizuki; Tatsuo Hosoya; Tomohiro Nakayama; Norio Yamamoto; Yoshio Higaki; Toshiko Shimizu Background: Although hypertension is commonly found in patients with autosomal dominant polycystic kidney disease (ADPKD...