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Keywords: Transgenic mouse models
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Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2010) 7 (1-3): 28–31.
Published Online: 13 February 2010
...Astrid Sydow; Eva-Maria Mandelkow Background: Aggregates of the tau protein are a hallmark of Alzheimer’s and several other neurodegenerative diseases. Various transgenic mouse models have been generated to study the aggregation process. Since wild-type tau is highly soluble and does not aggregate...