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Keywords: Spatial memory
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Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2012) 11 (1): 33–41.
Published Online: 24 May 2012
... by evidence of increased accumulation of Aβ, microglial activation and expression of IL-1β. Accumulation of Aβ was coupled with an increase in expression of BACE-1 and a decrease in insulin-degrading enzyme (IDE). Conclusion: The results indicate that the observed impairment in spatial memory in female APP...
Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2010) 7 (1-3): 148–152.
Published Online: 03 March 2010
... subtests. The hippocampal MCI group performed poorer than the nonhippocampal MCI group and similarly to the AD group. The ApoE4+ group was as bad as the AD group when compared with the E4– group. Conclusion: aMCI subjects represent a very heterogeneous population, and spatial memory or cued recall...
Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2005) 2 (1): 6–15.
Published Online: 10 August 2005
...-PCR analyses showed normal gross hippocampal morphology and unaltered expression of three genes involved in inflammatory responses in PS1 KI mice. These results show hippocampal spatial memory impairments caused by the PS1 M146V mutation and age-related deterioration of the memory impairment...