... that modulation and expression of pathogenetically important proteins resemble human brain pathology and functional deficits in the expected morphological and temporal pattern. Objective: The real usefulness of these models should be discussed from an objective point of view. Results: Not a single one...

... Biomarker Parkinson s disease Diagnosis Pathology Abstract A biomarker (biological marker) is a characteristic that is ob- jectively measured and evaluated as an indicator of normal biological processes, pathogenetic processes or pharmaco- logical responses to a therapeutic intervention. Expecta...