...Philippe Voruz; Didier Grandjean; Sophie Drapier; Dominique Drapier; Marc Vérin; Julie Anne Péron Introduction: Recently, studies have suggested a role of motor symptom asymmetry on impaired emotional recognition abilities in Parkinson’s disease with a greater vulnerability in patients...

... online suppl. material, see https://doi.org/10.1159/000540105 ). Parkinson’s disease DAT-SPECT imaging Dopamine Movement disorders Parkinsonian disorders Parkinson’s disease (PD) is characterized pathologically by the loss of dopaminergic neurons [ 1 ]. PD is diagnosed clinically...

... disease and other dementias), Parkinson’s disease and Parkinsonism, and multiple sclerosis in the Spanish-Portuguese cross-border border region in 2020. It includes Bragança and Guarda Districts (Portugal) and Salamanca (Castilla y León, Spain). Results: Neurodegenerative diseases accounted for 1.85...

...Konstantinos I. Tsamis; Per Odin; Angelo Antonini; Heinz Reichmann; Spyridon Konitsiotis Background: Technological evolution leads to the constant enhancement of monitoring systems and recording symptoms of diverse disorders. Summary: For Parkinson’s disease, wearable devices empowered with machine...

... process, influenced by working memory control processes, including recognition of semantic properties of items by which subjects generate a semantic structure of engrams. The aim of the study was to investigate the verbal learning strategies of individuals with Parkinson’s disease (PD). Methods: Thirty...

... of this study was to examine, within an Italian cohort of non-demented Parkinson’s disease (PD) patients, the ecological validity of the Montreal Cognitive Assessment (MoCA) by assessing its association with (1) functional independence (FI), (2) quality of life (QoL), and (3) behavioural-psychological (BP...

...Landis E. Llewelyn; Myriam Kornisch; Hyejin Park; Toshikazu Ikuta Background: While the hippocampus is not part of the nigrostriatal dopaminergic pathway, influence of Parkinson’s disease (PD) on the hippocampus has been consistently implicated. However, it is not clear how the hippocampal changes...

... dysregulation in explaining glutamatergic synaptic dysfunction observed in α-synucleinopathies such as Parkinson’s disease. [email protected] 28 12 2021 10 06 2022 8 08 2022 © 2022 S. Karger AG, Basel Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved...

...Edoardo Nicolò Aiello; Margherita Grosso; Claudia Caracciolo; Adele Andriulo; Simona Buscone; Monica Ottobrini; Claudio Luzzatti Background: In Parkinson’s disease (PD), verb-naming tasks (VNTs) have been proposed as superior to noun-naming ones in detecting language deficits, although...

... Padovani Introduction: Previous studies reported increased plasma levels of cystatin C (Cys-C) in Parkinson’s disease (PD) and claimed for a possible association with disease severity and progression. The aim of this study was to evaluate plasma Cys-C in PD and healthy controls (HC) and test its...

...Michaela Kaiserova; Monika Chudackova; Hana Prikrylova Vranova; Katerina Mensikova; Anetta Kastelikova; David Stejskal; Petr Kanovsky Background: Various cerebrospinal fluid (CSF) biomarkers are studied in Parkinson’s disease (PD) and atypical parkinsonian syndromes (APS). Several studies found...

.... In fact, several epidemiologic studies indicate a decreased incidence of most cancer types in Parkinson’s disease (PD) patients and some PD genes are involved in cancer networks. Objective: The aim of this study is to assess the influence of several factors in the risk of cancer in a cohort of 753 PD...

...Mutsumi Iijima; Mikio Osawa; Sayuri Yasuda; Kazuo Kitagawa Background: Excessive daytime sleepiness (EDS) in Parkinson’s disease (PD) may occur because of dysfunction on the brain areas in controlling wakefulness; however, the pathophysiology of EDS in PD has not been completely clarified. The Pb...

...Aida Arroyo-Ferrer; Jorge Andreo; José A. Periáñez; Marcos Ríos-Lago; Genny Lubrini; Jaime Herreros-Rodríguez; Juan García-Caldentey; Juan Pablo Romero Background: Parkinson’s disease (PD) patients are known to suffer from subtle cognitive and balance deficits from the early stages although...

...Songzhe He; Shan Zhong; Gang Liu; Jun Yang Background: Parkinson’s disease (PD) is a multifactorial, chronic, and progressive neurodegenerative disease. α-Synuclein (α-syn), which is the main protein component of Lewy bodies, plays an important role in the pathological hallmarks of PD. However...

... and Parkinson’s disease. Methods: We conducted a population-based case-control study of incident Parkinson’s disease in 2009 Medicare beneficiaries age 66–90 years (89,790 cases, 118,095 randomly selected comparable controls). We classified beneficiaries with any diagnosis code for “herpes simplex” and/or “herpes...

...Muhammad Kashif; Ashfaq Ahmad; Muhammad Ali Mohseni Bandpei; Syed Amir Gillani; Asif Hanif; Humaira Iram Background: Parkinson’s disease (PD) is one of the most common neurological disorders, of insidious onset, with major motor symptomatology including bradykinesia, rest tremor, rigidity...

...Minghao Zhang; Qingping He; Guisheng Chen; P. Andy Li Background: Parkinson’s disease (PD) is characterized by the selective death of dopaminergic neurons in the substantia nigra. Recently, NLRP3 inflammasome and pyroptosis were found to be associated with PD. Cyclosporine A (CsA...

...Sai Batchu Introduction: Although not considered a primary cause, neuroinflammation is associated with many neurodegenerative disorders, including Parkinson’s disease (PD). Methods: To elucidate potential immune involvement in PD, the present study imputed immune cell abundances from bulk RNA...

...Shen-Yang Lim; Jia Lun Lim; Azlina Ahmad-Annuar; Katja Lohmann; Ai Huey Tan; Kai Bin Lim; Yi Wen Tay; Yee Lee Shing; Kalai Arasu Muthusamy; Peter Bauer; Arndt Rolfs; Christine Klein Pathogenic and risk variants in the LRRK2 gene are among the main genetic contributors to Parkinson’s disease (PD...