... found that OxAc/rGOT treatment provides significant neuroprotection to spinal cord motor neurons. It also slows down the development of motor weakness and prolongs survival. Conclusion: In this study we bring evidence that the administration of Glu scavengers to rats with sporadic ALS inhibited...

... mimetics. These data suggest that the combination of anti-inflammatory and neuroprotective activities of apoE mimetics represents a new generation of potential therapeutics for AD. 22 06 2011 7 11 2011 9 2 2012 © 2012 S. Karger AG, Basel 2012 Copyright / Drug Dosage / Disclaimer...

.... Hysterectomy Oophorectomy Menopause Estrogen Neuroprotection Dementia Cognitive impairment National Institutes of Health (NIH) 10.13039/100000002 Diseases Neurodegenerative Dis 2012;10:175 178 DOI: 10.1159/000334764 Received: July 1, 2011 Accepted after revision: October 28, 2011...

... catalytic activity. Objective: In this study, the aim was to expand the pharmacological profiling of huprine-tacrine heterodimers investigating their effect on muscarinic M 1 receptors as well as their neuroprotective effects against an oxidative insult. Methods: Sprague-Dawley rat hippocampus homogenates...

...Orly Weinreb; Tamar Amit; Silvia Mandel; Moussa B.H. Youdim Our novel multimodal brain-permeable iron-chelating compounds M30 and HLA20 were demonstrated to possess neuroprotective/neurorescue activities in vitro and in vivo against several insults applicable to various neurodegenerative diseases...

..., instructions or products referred to in the content or advertisements. Iron Iron chelator Neuroprotection Amyotrophic lateral sclerosis Oxidative stress Diseases Original Paper Neurodegenerative Dis 2011;8:310 321 DOI: 10.1159/000323469 Received: July 21, 2010 Accepted after revision: December 9...

..., D.C., USA; b The Research Institute of the McGill University Health Centre, c Department of Medicine and d Pharmacology and Therapeutics and Biochemistry, McGill University, Montreal, Que., Canada Key Words Alzheimer s disease -Amyloid peptide Mitochondria Neuroprotection Neurosteroids...

...Walter A. Rocca; Brandon R. Grossardt; Lynne T. Shuster Background: The concept of neuroprotective effects of estrogen in women remains controversial. Objective: To explore the timing hypothesis in relation to cognitive aging and dementia. Methods: We reviewed existing literature, conducted some...

...Seyyed Amirhossein Fazeli Increasing evidence has shown that diabetes may be associated with learning and memory deficits in humans. These cognitive disorders, called ‘diabetic encephalopathy’, can impair the daily performance of diabetic individuals. In recent years, some neuroprotective measures...

...Walter A. Rocca; Brandon R. Grossardt; Demetrius M. Maraganore Background: The evidence for a neuroprotective effect of estrogen in women remains controversial. Objective: We studied the long-term risk of parkinsonism and of cognitive impairment or dementia in women who underwent oophorectomy...

... disease Neuroprotection Ubiquitin-proteasome system Therapeutic approaches α-Synuclein 12 07 2007 16 07 2007 29 2 2008 Diseases Review Neurodegenerative Dis 2008;5:321 338 DOI: 10.1159/000119459 Received: July 12, 2007 Accepted: July 16, 2007 Published online: February 29, 2008...

...- and RNA-induced neurodegeneration, as well as discovery of novel drug targets. We review here the various fly models of neurodegenerative conditions, and summarise the novel insights that the fly has contributed to the field of neuroprotection and neurodegeneration. 11 1 2007 © 2006 S. Karger...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Erythropoietin Hypoxia Neuroprotection Neuronal regeneration Ischemia Stroke Stem cell therapy Angiogenesis Neurogenesis Diseases Signaling and Stem Cells Neurodegenerative Dis 2006;3:87 93...