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Keywords: Neurodegeneration
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Journal Articles
Neurodegener Dis (2022) 22 (3-4): 91–103.
Published Online: 13 April 2023
... or advertisements. 2023 SARS-CoV-2 COVID-19 Delirium Acute encephalopathy Dementia Neurodegeneration Neurovascular unit COVID-19 pandemic has impacted our society, requiring urgent action and adaptation, catalyzing the scientific endeavor, and allowing the achievement of solutions...
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Neurodegener Dis (2017) 17 (4-5): 181–198.
Published Online: 11 May 2017
... to in the content or advertisements. Mouse model Brain-derived neurotrophic factor Neurodegeneration Dorsal root ganglion Cerebellar nucleus Ataxia Iron deposition Mouse models of neurodegenerative diseases are very useful tools in investigating etiology, pathophysiology and treatment...
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Neurodegener Dis (2017) 17 (4-5): 155–165.
Published Online: 03 May 2017
... and neurodegeneration, and we additionally provide exemplar cases of cerebellar dysfunction in neurodegenerative disorders. Results: Comparisons between normal function and neurodegenerative disease states emphasize how normal organization of the cerebellum is altered in neurodegenerative disease states. We illustrate...
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Neurodegener Dis (2016) 17 (1): 38–43.
Published Online: 10 September 2016
... Biomarker Nigrostriatal system Neurodegeneration Parkinson’s disease Parkinson's disease (PD) is an age-related neurodegenerative disorder associated with a specific pattern of brain pathology including, but not restricted to, a prominent loss of dopaminergic neurons in the substantia nigra...
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Neurodegener Dis (2016) 16 (3-4): 260–272.
Published Online: 16 March 2016
..., instructions or products referred to in the content or advertisements. Cortical neurons Mast syndrome Maspardin ACP33 SPG21 –/– Neurodegeneration Paraplegia Hereditary spastic paraplegias (HSPs) are a genetically diverse family of disorders presenting a spectrum of symptoms...
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Neurodegener Dis (2016) 16 (3-4): 172–178.
Published Online: 28 November 2015
... to neurodegeneration. In particular, human haemochromatosis protein (HFE) is involved in iron metabolism, and HFE H63D polymorphism has been related to the risk of amyotrophic lateral sclerosis and Alzheimer's disease. Recently, iron accumulation in the basal ganglia of frontotemporal lobar degeneration (FTLD...
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Neurodegener Dis (2014) 13 (2-3): 61–63.
Published Online: 02 October 2013
... and PS conditional knockout mice exhibit similar deficits in memory and age-dependent neurodegeneration are consistent with the notion that γ-secretase-dependent activities of PS are required for the maintenance of memory and neuronal survival, though the γ-secretase physiological substrates, Notch...
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Neurodegener Dis (2014) 13 (2-3): 96–98.
Published Online: 07 August 2013
... Mechanism of neurodegenerative diseases Neurodegeneration Protein misfolding The β-amyloid precursor protein (APP) is a 110- to 130-kDa integral type I transmembrane glycoprotein that has been extensively studied for its role in Alzheimer's disease (AD). APP belongs to a family of evolutionarily...
Journal Articles
Neurodegener Dis (2014) 13 (2-3): 189–191.
Published Online: 07 August 2013
.... Brain iron Amyloid plaques Iron deposition Neurodegeneration In summary, recent MRI developments have enabled the quantitative assessment of iron levels in vivo. Obviously, iron accumulation in deep gray matter is an unspecific finding in AD because it is also frequently observed in other...
Journal Articles
Neurodegener Dis (2013) 12 (4): 165–176.
Published Online: 26 April 2013
... neurodegeneration during waking and counteractive processes during the relatively tonically quiescent phase of non-REM sleep and an active ‘rescue' phase of synaptic remodelling associated with REM sleep. Cumulative synaptic dysfunction associated with waking directs pro-inflammatory and pro-fibrillogenic...