...Chang-E. Zhang; Xifei Yang; Lingyun Li; Xiaojing Sui; Qing Tian; Wei Wei; Jianzhi Wang; Gongping Liu Hypoxia was shown to be associated with an increased risk of Alzheimer's disease (AD). The effects of hypoxia on the development of AD pathology and spatial memory ability and the possible molecular...

...Emilie Pacary; Edwige Petit; Myriam Bernaudin Hypoxia and ischemia in the brain often result in brain dysfunctions and neuronal death during both the neonatal and adult periods. Though the mechanisms contributing to brain injury secondary to hypoxia-ischemia are more clearly defined...

...Li Zhou; Carol A. Miller In the adult nervous system, neuronal subpopulations sustain a hierarchical pattern of selective vulnerability to hypoxia. Hypoxia also activates quiescent neural progenitor cells (NPCs) resulting in their amplification and subsequent differentiation into neurons and glia...

...) production, and assessed the influence of the PS1Δ9 FAD mutation on these effects. Method: For this purpose, we exposed stably transfected H4 human neuroglioma cells to conditions consistent with hypocapnia (PCO 2 <40 mm Hg) and hypocapnia plus hypoxia (PO 2 <21%). Results: Hypocapnia (20 mm Hg CO 2...