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1-13 of 13
Keywords: Hippocampus
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Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2022) 22 (1): 29–33.
Published Online: 29 November 2022
...Landis E. Llewelyn; Myriam Kornisch; Hyejin Park; Toshikazu Ikuta Background: While the hippocampus is not part of the nigrostriatal dopaminergic pathway, influence of Parkinson’s disease (PD) on the hippocampus has been consistently implicated. However, it is not clear how the hippocampal changes...
Journal Articles
Subject Area:
Topic Article Package: Moksha
,
Further Areas
,
Geriatrics and Gerontology
,
Neurology and Neuroscience
Sven Haller, Marie-Louise Montandon, Cristelle Rodriguez, Valentina Garibotto, François R. Herrmann, Panteleimon Giannakopoulos
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2019) 19 (3-4): 139–147.
Published Online: 17 December 2019
..., instructions or products referred to in the content or advertisements. Aging Hippocampus Amyloid APOE Hippocampal volume loss (HVL), brain amyloid accumulation derived from brain amyloid PET, and APOE status are well-established biomarkers in the domain of cognitive decline and Alzheimer...
Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2018) 18 (1): 49–56.
Published Online: 07 February 2018
... cells CD3 Amyloid Tau AT8 6E10 Hippocampus Mid frontal gyrus Confocal Microscopy. Following standard deparaffinization and rehydration steps, hippocampal AD brain paraffin sections (20-μm thick) were pretreated with citrate antigen retrieval buffer for 20 min at 95°C as previously...
Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2017) 17 (6): 235–241.
Published Online: 26 July 2017
... and their association with clinical and neuropathological variables are lacking during the clinical progression of Alzheimer disease (AD). Methods: We quantified levels of the GSAP precursor (98 kDa) and its active form (16 kDa) in the frontal cortex and hippocampus, areas displaying extensive Aβ and neurofibrillary...
Journal Articles
Ricardo Taipa, Paulo Brochado, Andrew Robinson, Inês Reis, Patrício Costa, David M. Mann, Manuel Melo Pires, Nuno Sousa
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2017) 17 (4-5): 145–154.
Published Online: 27 April 2017
... overlap between AD and FTLD-TDP, namely in memory deficits. Alzheimer disease Frontotemporal lobar degeneration Microglia Hippocampus Memory Microglial cells are the predominant resident immune cells of the central nervous system and are considered as tissue-resident macrophages...
Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2014) 13 (2-3): 86–92.
Published Online: 24 September 2013
... affected by apoE4. The suggestion that the behavioral impairments of the apoE4 mice are related to the hippocampal neuropathology of these mice is further supported by the fear conditioning test. This test revealed that the performance of the apoE4 mice in the contextual component, which is hippocampus...
Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2012) 11 (2): 93–101.
Published Online: 03 October 2012
... trial-by-trial feedback, while other forms of learning, such as hippocampal-dependent episodic memory, remain intact. Interestingly, it has been suggested that the striatum and the hippocampus compete during learning, leading to the intriguing prediction that the striatal disruption in PD could lead...
Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2013) 12 (2): 91–102.
Published Online: 30 August 2012
.... Parkinson’s disease Lewy body dementia Neurofibrillary tangles Hippocampus Memory Hyperphosphorylation and formation of paired helical filaments constitute the other hallmark of Alzheimer's disease besides amyloid plaques, while Parkinson's disease (PD) and Lewy body disease are characterized...
Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2012) 10 (1-4): 216–219.
Published Online: 04 February 2012
... occur during the earliest stages of cognitive decline remains unclear. We examined protein levels of presynaptic synaptophysin (SYP) and synaptotagmin (SYT), and postsynaptic drebrin (DRB), a marker for dendritic spine plasticity, in the hippocampus of people with an antemortem clinical diagnosis...
Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2011) 9 (1): 31–37.
Published Online: 20 October 2011
...: To investigate changes in TNAP activity in the hippocampus in both sporadic and familial AD, and to examine whether changes in neuronal TNAP are reflected systemically by looking at changes in plasma TNAP activity in AD. Methods: We measured the activity of TNAP in the hippocampus in sporadic AD, familial AD...
Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2010) 6 (5-6): 221–229.
Published Online: 09 September 2009
...Jurjen W. Westra; Serena Barral; Jerold Chun Alzheimer’s disease (AD) is characterized by extensive neuronal death in distinct brain regions, including the frontal cortex and hippocampus, although the specific mechanisms of neuronal degeneration in AD remain a topic of intense scientific pursuit...
Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2006) 2 (5): 273–276.
Published Online: 22 February 2006
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Amyloid Dementia Vaccination Immunization Hippocampus Diseases Special Topic Section: Immunotherapies and Related...
Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2005) 2 (1): 6–15.
Published Online: 10 August 2005
..., Md., USA Received: March 3, 2005 Accepted: May 9, 2005 Key Words Knock-in mouse model Brain Water maze task - Secretase Spatial memory Hippocampus Presenilin Abstract Mutations in presenilins (PS) 1 and 2 are the major cause of familial Alzheimer s disease. Conditional inactivation...