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Keywords: Glycolytic inhibition
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Journal Articles
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2012) 11 (1): 49–58.
Published Online: 24 May 2012
...) attenuated the neuronal death induced by these toxins. The increase in [Zn 2+ ] i preceded a reduction in the NAD + /NADH ratio that caused a reversible glycolytic inhibition. Pyruvate, nicotinamide and NAD + reversed the reductions in the NAD + /NADH ratio, glycolysis and neuronal death after challenge...