...Shen-Yang Lim; Jia Lun Lim; Azlina Ahmad-Annuar; Katja Lohmann; Ai Huey Tan; Kai Bin Lim; Yi Wen Tay; Yee Lee Shing; Kalai Arasu Muthusamy; Peter Bauer; Arndt Rolfs; Christine Klein Pathogenic and risk variants in the LRRK2 gene are among the main genetic contributors to Parkinson’s disease (PD...

...Jessica Mandrioli; Bernhard Michalke; Nikolay Solovyev; Peter Grill; Federica Violi; Christian Lunetta; Amelia Conte; Valeria Ada Sansone; Mario Sabatelli; Marco Vinceti Background: Although an increasing role of genetic susceptibility has been recognized, the role of environmental risk factors...

... cases are sporadic, hereditary tauopathies have also been reported. Summary: In this article, we review genetic disorders in which tau pathology has been reported and present two novel families with primary tauopathies. Mutations in the microtubule-associated protein tau gene (MAPT) cause a small subset...

...Shinsuke Fujioka; Zbigniew K. Wszolek Background: Major progress in genetic studies of Parkinson’s disease (PD) and parkinsonism has been achieved in the last two decades. Objective: We provide a brief review of the current status of PARK and non-PARK loci/genes, and discuss two new genes: eIF4G1...