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Keywords: GRN
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Journal Articles
Roberta Ghidoni, Elena Stoppani, Giacomina Rossi, Elena Piccoli, Valentina Albertini, Anna Paterlini, Michela Glionna, Eleonora Pegoiani, Luigi F. Agnati, Chiara Fenoglio, Elio Scarpini, Daniela Galimberti, Michela Morbin, Fabrizio Tagliavini, Giuliano Binetti, Luisa Benussi
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2012) 9 (3): 121–127.
Published Online: 26 November 2011
..., attention was drawn to a role for progranulin in the central nervous system with the identification of mutations in the progranulin gene (GRN) as an important cause of frontotemporal lobar degeneration. GRN mutations are associated with a strong reduction of circulating progranulin and widely variable...
