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Keywords: Frontotemporal dementia
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Journal Articles
Neurodegener Dis (2019) 18 (5-6): 239–253.
Published Online: 18 October 2018
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Amyotrophic lateral sclerosis C9orf72 repeat expansion Frontotemporal dementia Huntington disease genetic testing...
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Neurodegener Dis (2011) 8 (5): 289–295.
Published Online: 11 February 2011
... for Neurodegenerative Disorders, University of Milan, Milan, Italy Key Words Frontotemporal lobar degeneration Frontotemporal dementia Progranulin MAPT haplotype VEGF polymorphisms APOE Abstract Background: Ruling out predictors of survival in frontotemporal lobar degeneration (FTLD) is a clinical challenge...
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Neurodegener Dis (2011) 8 (3): 149–152.
Published Online: 14 September 2010
...Jonathan D. Rohrer; Dominic Paviour; Jana Vandrovcova; John Hodges; Rohan de Silva; Martin N. Rossor Background: MAPT mutations are associated with disorders within the frontotemporal lobar degeneration spectrum. The usual presenting syndrome is behavioural variant frontotemporal dementia, although...
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Neurodegener Dis (2010) 7 (1-3): 99–102.
Published Online: 18 February 2010
...Dominik Paquet; Bettina Schmid; Christian Haass Our ageing society is confronted with a dramatic increase in patients suffering from tauopathies such as Alzheimer’s disease, frontotemporal dementia and others. Typical neuropathological lesions including tangles composed of hyperphosphorylated tau...
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Neurodegener Dis (2010) 7 (1-3): 10–12.
Published Online: 13 February 2010
...-term cultures. To determine tau toxicity, K369I mutant tau mice were established as a model of frontotemporal dementia, analyzed biochemically and compared with human diseased brain. Results: Oligomeric and fibrillar Aβ42 were both toxic, although to different degrees. Human amylin shared toxicity...
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Neurodegener Dis (2007) 4 (2-3): 236–253.
Published Online: 29 June 2007
... Alzheimer’s disease. The involvement of tau in neurodegeneration has been clarified by the identification of genetic mutations in the tau gene in cases with familial frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Although the mechanism through which tau mutations lead to neuronal...
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