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Keywords: CYP2D6
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Journal Articles
Influence of Pharmacogenetic Factors on Alzheimer’s Disease Therapeutics
Available to Purchase
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2008) 5 (3-4): 176–178.
Published Online: 06 March 2008
... response in AD is genotype specific, with APOE-4/4 carriers as the worst responders to conventional treatments. In addition, about 10–20% of Caucasians are carriers of defective CYP2D6 polymorphic variants that alter the metabolism and effects of AD drugs and many psychotropic agents currently administered...
