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1-4 of 4
Keywords: APOE
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Journal Articles
Hippocampal Volume Loss, Brain Amyloid Accumulation, and APOE Status in Cognitively Intact Elderly Subjects
Available to PurchaseSubject Area:
Topic Article Package: Moksha
, Further Areas
, Geriatrics and Gerontology
, Neurology and Neuroscience
Sven Haller, Marie-Louise Montandon, Cristelle Rodriguez, Valentina Garibotto, François R. Herrmann, Panteleimon Giannakopoulos
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2019) 19 (3-4): 139–147.
Published Online: 17 December 2019
...Sven Haller; Marie-Louise Montandon; Cristelle Rodriguez; Valentina Garibotto; François R. Herrmann; Panteleimon Giannakopoulos Background: Hippocampal volume loss (HVL), PET-documented brain amyloid accumulation, and APOE-ε4 status are predictive biomarkers of the transition from mild cognitive...
Journal Articles
The Effect of TOMM40 Poly-T Repeat Lengths on Age of Onset and Cerebrospinal Fluid Biomarkers in Finnish Alzheimer's Disease Patients
Available to PurchaseSeppo Helisalmi, Anette Hall, Esa-Heikki Meriläinen, Viljami Väisänen, Anne Maria Koivisto, Sanna-Kaisa Herukka, Marjo Laitinen, Hilkka Soininen, Mikko Hiltunen
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2015) 14 (4): 204–208.
Published Online: 04 December 2014
...Seppo Helisalmi; Anette Hall; Esa-Heikki Meriläinen; Viljami Väisänen; Anne Maria Koivisto; Sanna-Kaisa Herukka; Marjo Laitinen; Hilkka Soininen; Mikko Hiltunen Background: Poly-T repeat lengths of rs10524523 in TOMM40 together with APOE polymorphism have been reported to affect the risk of late...
Journal Articles
Genetic Background Predicts Poor Prognosis in Frontotemporal Lobar Degeneration
Available to PurchaseB. Borroni, M. Grassi, S. Archetti, A. Papetti, R. Del Bo, C. Bonvicini, G.P. Comi, M. Gennarelli, G. Bellelli, M. Di Luca, A. Padovani
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2011) 8 (5): 289–295.
Published Online: 11 February 2011
... study. A clinical evaluation and a standardized assessment were carried out. Each patient underwent blood sampling for genetic testing, and mutations within the progranulin (PGRN) gene, microtubule-associated protein tau (MAPT) haplotype, apolipoprotein E (APOE) genotype and 4 vascular endothelial...
Journal Articles
Influence of Pharmacogenetic Factors on Alzheimer’s Disease Therapeutics
Available to Purchase
Journal:
Neurodegenerative Diseases
Neurodegener Dis (2008) 5 (3-4): 176–178.
Published Online: 06 March 2008
... response in AD is genotype specific, with APOE-4/4 carriers as the worst responders to conventional treatments. In addition, about 10–20% of Caucasians are carriers of defective CYP2D6 polymorphic variants that alter the metabolism and effects of AD drugs and many psychotropic agents currently administered...
