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Keywords: 3-Nitropropionic acid
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Journal Articles

Melatonin Reduces Projection Neuronal Injury Induced by 3-Nitropropionic Acid in the Rat Striatum

Subject Area:
Further Areas , Geriatrics and Gerontology , Neurology and Neuroscience
Shuhua Mu, Erjian Lin, Bingbing Liu, Yuxin Ma, Lisi OuYang, Youlan Li, Si Chen, Jian Zhang, Wanlong Lei
Journal: Neurodegenerative Diseases
Neurodegener Dis (2014) 14 (3): 139–150.
https://doi.org/10.1159/000365891
Published Online: 22 October 2014
... of experimental rats and injury of striatal interneurons induced by 3-nitropropionic acid. The present study aimed to further determine the effect of melatonin on the injury of striatal projection neurons induced by 3-nitropropionic acid. Methods: Classic histology, immunohistochemistry, Western blotting...
View article titled, Melatonin Reduces Projection Neuronal Injury Induced by <span class="search-highlight">3</span>-<span class="search-highlight">Nitropropionic</span> <span class="search-highlight">Acid</span> in the Rat Striatum
Open the PDF for Melatonin Reduces Projection Neuronal Injury Induced by <span class="search-highlight">3</span>-<span class="search-highlight">Nitropropionic</span> <span class="search-highlight">Acid</span> in the Rat Striatum in another window
Journal Articles

Mitochondrial Inhibitor Models of Huntington’s Disease and Parkinson’s Disease Induce Zinc Accumulation and Are Attenuated by Inhibition of Zinc Neurotoxicity in vitro or in vivo

Subject Area:
Further Areas , Geriatrics and Gerontology , Neurology and Neuroscience
Christian T. Sheline, Julia Zhu, Wendy Zhang, Chunxiao Shi, Ai-Li Cai
Journal: Neurodegenerative Diseases
Neurodegener Dis (2012) 11 (1): 49–58.
https://doi.org/10.1159/000336558
Published Online: 24 May 2012
... lesion and restored behavioral scores. Conclusions: Together, these studies suggest that Zn 2+ accumulation caused by MPP + and 3-NPA is a novel preventable mechanism of the resultant neurotoxicity. 3-Nitropropionic acid 6-Hydroxydopamine N-methyl-4-phenylpyridium Zinc neurotoxicity Glycolytic...
View article titled, Mitochondrial Inhibitor Models of Huntington’s Disease and Parkinson’s Disease Induce Zinc Accumulation and Are Attenuated by Inhibition of Zinc Neurotoxicity in vitro or in vivo
Open the PDF for Mitochondrial Inhibitor Models of Huntington’s Disease and Parkinson’s Disease Induce Zinc Accumulation and Are Attenuated by Inhibition of Zinc Neurotoxicity in vitro or in vivo in another window
Journal Articles

N -Acetylcysteine Reverses Mitochondrial Dysfunctions and Behavioral Abnormalities in 3-Nitropropionic Acid-Induced Huntington’s Disease

Subject Area:
Further Areas , Geriatrics and Gerontology , Neurology and Neuroscience
Rajat Sandhir, Aditi Sood, Arpit Mehrotra, Sukhdev S. Kamboj
Journal: Neurodegenerative Diseases
Neurodegener Dis (2012) 9 (3): 145–157.
https://doi.org/10.1159/000334273
Published Online: 09 February 2012
...Rajat Sandhir; Aditi Sood; Arpit Mehrotra; Sukhdev S. Kamboj Mitochondrial dysfunction is a major event involved in the pathogenesis of Huntington’s disease (HD). The present study evaluates the role of N -acetyl- L -cysteine (NAC) in preventing mitochondrial dysfunctions in a 3-nitropropionic acid...
View article titled, N -Acetylcysteine Reverses Mitochondrial Dysfunctions and Behavioral Abnormalities in <span class="search-highlight">3</span>-<span class="search-highlight">Nitropropionic</span> <span class="search-highlight">Acid</span>-Induced Huntington’s Disease
Open the PDF for N -Acetylcysteine Reverses Mitochondrial Dysfunctions and Behavioral Abnormalities in <span class="search-highlight">3</span>-<span class="search-highlight">Nitropropionic</span> <span class="search-highlight">Acid</span>-Induced Huntington’s Disease in another window