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Keywords: β-Sheet
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Journal Articles
Neurodegener Dis (2012) 10 (1-4): 298–300.
Published Online: 09 December 2011
..., we have developed novel cell culture models, including primary neurons prepared from PrP-deficient mice. Using these approaches we have been able to show that PrP C can interact with and mediate toxic signaling of various β-sheet-rich conformers of different origins, including amyloid β, suggesting...