Abstract
Craniosynostosis is a medical condition caused by the early fusion of the cranial joint. The finite element method (FEM) is a computational technique that can answer a variety of “what if” questions in relation to the biomechanics of this condition. The aim of this study was to review the current literature that has used FEM to investigate the biomechanics of any aspect of craniosynostosis, being its development or its reconstruction. This review highlights that a relatively small number of studies (n = 10) has used FEM to investigate the biomechanics of craniosynostosis. Current studies set a good foundation for the future to take advantage of this method and optimize reconstruction of various forms of craniosynostosis.
References
1.
Abbott A, Netherway DJ, Niemann DB, Clark B, Yamamoto M, et al: CT-determined intracranial volume for a normal population. J Craniofac Surg 11:211-223 (2000).
2.
Al-Rekabi Z, Cunningham ML, Sniadecki NJ: Cell mechanics of craniosynostosis. ACS Biomater Sci Eng 3:2733-2743 (2017).
3.
Borghi A, Rodriguez-Florez N, Rodgers W, James G, Hayward R, et al: Spring assisted cranioplasty: a patient specific computational model. Med Eng Phys 53:58-65 (2018).
4.
Clayman MA, Murad GJ, Steele MH, Seagle MB, Pincus DW: History of craniosynostosis surgery and the evolution of minimally invasive endoscopic techniques: the University of Florida experience. Ann Plast Surg 58:285-287 (2007).
5.
Coats B, Margulies SS: Material properties of human infant skull and suture at high rates. J Neurotrauma 23:1222-1232 (2006).
6.
Cornelissen M, Ottelander Bd, Rizopoulos D, van der Hulst R, Mink van der Molen A, et al: Increase of prevalence of craniosynostosis. J Craniomaxillofac Surg 44:1273-1279 (2016).
7.
Dai H, Pear N, Smith W, Duncan C: A 3D Morphable model of craniofacial shape and texture variation. IEEE International Conference on Computer Vision, Oct 22-29, Venice (2017).
8.
Dekaban AS: Tables of cranial and orbital measurements, cranial volume, and derived indexes in males and females from 7 days to 20 years of age. Ann Neurol 2:485-491 (1977).
9.
Dixit P, Liu GR: A review on recent development of finite element models for head injury simulations. Arch Computat Methods Eng 24:979-1031 (2017).
10.
Fagan MJ: Finite Element Analysis: Theory and Practice (Longman Scientific and Technical, Harlow 1992).
11.
Gerety PA, Basta MN, Fischer JP, Taylor JA: Operative management of nonsyndromic sagittal synostosis: a head-to-head meta-analysis of outcomes comparing 3 techniques. J Craniofac Surg 26:1251-1257 (2015).
12.
Ghajari M, Hellyer PJ, Sharp DJ: Computational modelling of traumatic brain injury predicts the location of chronic traumatic encephalopathy pathology. Brain 140:333-343 (2017).
13.
Hardy CH, Marcal PV: Elastic analysis of a skull. J Appl Mech 40:838-842 (1973).
14.
Henderson JH, Chang LY, Song HM, Longaker MT, Carter DR: Age-dependent properties and quasi-static strain in the rat sagittal suture. J Biomech 38:2294-2301 (2005).
15.
Herring SW: Mechanical influences on suture development and patency. Front Oral Biol 12:41-56 (2008).
16.
Hopper RA, Grant GA, Ellenbogen RG: Controversies in the management of craniosynostosis. Sem Neurosurg 13:81-95 (2002).
17.
Horgan TJ, Gilchrist MD: The creation of three-dimensional finite element models for simulating head impact biomechanics. Int J Crash 8:353-366 (2003).
18.
Huiskes R, Chao EY: A survey of finite element analysis in orthopedic biomechanics: the first decade. J Biomech 16:385-409 (1983).
19.
Imai K, Tsujiguchi K, Toda C, Enoki E, Sung KC, et al: Reduction of operating time and blood transfusion for craniosynostosis by simulated surgery using three-dimensional solid models. Neurol Med Chir (Tokyo) 39:423-426 (1999).
20.
Iyer RR, Wu A, Macmillan A, Musavi L, Cho R, et al: Use of computer-assisted design and manufacturing to localize dural venous sinuses during reconstructive surgery for craniosynostosis. Childs Nerv Syst 34:137-142 (2018).
21.
Jaslow CR, Biewener AA: Strain patterns in the horncores, cranial bones and sutures of goats (Capra hircus) during impact loading. J Zool 235:193-210 (1995).
22.
Jiang X, You J, Wang N, Shen Z, Li J: Skull mechanics study of PI procedure plan for craniosynostosis correction based on finite element method. 4th International Conference on Bioinformatics and Biomedical Engineering, June 10-12, Chengdu, (2010).
23.
Jimenez DF, Barone CM: Early treatment of coronal synostosis with endoscopy-assisted craniectomy and postoperative cranial orthosis therapy: 16-year experience. J Neurosurg Pediatr 12:207-219 (2013).
24.
Jin J, Shahbazi S, Lloyd J, Fels S, de Ribaupierre S, et al: Hybrid simulation of brain-skull growth. Simulation 90:3-10 (2014).
25.
Johnson D, Wilkie AOM: Craniosynostosis. Eur J Hum Genet 19:369-376 (2011).
26.
Khonsari RH, Olivier J, Vigneaux P, Sanchez S, Tafforeau P, et al: A mathematical model for mechanotransduction at the early steps of suture formation. Proc Biol Sci 280:20122670 (2013).
27.
Larysz D, Wolański W, Kawlewska E, Mandera M, Gzik M: Biomechanical aspects of preoperative planning of skull correction in children with craniosynostosis. Acta Bioeng Biomech 14:19-26 (2012).
28.
Lee C, Richtsmeier JT, Kraft RH: A computational analysis of bone formation in the cranial vault using a coupled reaction-diffusion-strain model. J Mech Med Biol 17:1750073 (2017).
29.
Lestrel PE: Some approaches toward the mathematical modeling of the craniofacial complex. J Craniofac Gene Dev Bio 9:77-91 (1989).
30.
Li X, Zhu W, He J, Di F, Wang L, et al: Application of computer assisted three-dimensional simulation operation and biomechanics analysis in the treatment of sagittal craniosynostosis. J Clin Neurosci 44:323-329 (2017).
31.
Libby J, Marghoub A, Johnson D, Khonsari R, Fagan MJ, Moazen M: Modelling human skull growth: a validated computational model. J R Soc Interface 14:20170202 (2017).
32.
Marghoub A, Libby J, Babbs C, Pauws E, Fagan MJ, Moazen M: Predicting calvarial growth in normal and craniosynostosis mice using a computational approach. J Anat 232:440-448 (2018).
33.
Margulies SS, Thibault KL: Infant skull and suture properties: measurements and implications for mechanisms of pediatric brain injury. J Biomech Eng 122:364-371 (2000).
34.
Mathijssen IMJ: Guideline for care of patients with the diagnoses of craniosynostosis: working group on craniosynostosis. J Craniofac Surg 26:1735-1807 (2015).
35.
McCarthy JG, Glasberg SB, Cutting CB, Epstein FJ, Grayson BH, et al: Twenty-year experience with early surgery for craniosynostosis: I. Isolated craniofacial synostosis-results and unsolved problems. Plast Reconstr Surg 96:272-283 (1995).
36.
McPherson GK, Kriewall TJ: Fetal head molding: an investigation utilizing a finite element model of the fetal parietal bone. J Biomech 13:17-26 (1980).
37.
Meehan M, Teschner M, Girod S: Three-dimensional simulation and prediction of craniofacial surgery. Orthod Craniofac Res 6 Suppl 1:102-107 (2003).
38.
Moazen M, Curtis N, O'Higgins P, Evans SE, Fagan MJ: Biomechanical assessment of evolutionary changes in the lepidosaurian skull. Proc Nat Acad Sci USA 106:8273-8277 (2009).
39.
Moazen M, Costantini D, Bruner E: A sensitivity analysis to the role of fronto-parietal suture in Lacerta bilineata: a preliminary finite element approach. Anat Rec (Hoboken) 296:198-209 (2013).
40.
Moazen M, Peskett E, Babbs C, Pauws E, Fagan MJ: Mechanical properties of calvarial bones in a mouse model for craniosynostosis. PLoS One 10:e0125757 (2015).
41.
Mommaerts M, Jans G, Vander Stoten J, Staels PF, Van der Perre G, Gobin R: On the assets of CAD planning for craniosynostosis surgery. J Craniofac Surg 12:547-554 (2001).
42.
Morriss-Kay GM, Wilkie AOM: Growth of the normal skull vault and its alteration in craniosynostosis: insights from human genetics and experimental studies. J Anat 207:637-653 (2005).
43.
Moss ML: Growth of the calvaria in the rat, the determination of osseous morphology. Am J Anat 94:333-361 (1954).
44.
Nagasao T, Miyamoto J, Uchikawa Y, Tamaki T, Yamada A, et al: A biomechanical study on the effect of premature fusion of the frontosphenoidal suture on orbit asymmetry in unilateral coronal synostosis. Cleft Palate Craniofac J 47:82-91 (2010).
45.
Nagasao T, Miyamoto J, Jiang H, Kaneko T, Tamaki T: Biomechanical analysis of the effect of intracranial pressure on the orbital distances in trigonocephaly. Cleft Palate Craniofac J 48:190-196 (2011).
46.
O'Higgins P, Cobb SN, Fitton LC, Gröning F, Phillips R, et al: Combining geometric morphometrics and functional simulation: an emerging toolkit for virtual functional analyses. J Anat 218:3-15 (2011).
47.
Opperman LA: Cranial sutures as intramembranous bone growth sites. Dev Dyn 219:472-485 (2000).
48.
Pan X, Qian Y, Yu J, Wang D, Tang Y, Shen G: Biomechanical effects of rapid palatal expansion on the craniofacial skeleton with cleft palate: a three-dimensional finite element analysis. Cleft Palate Craniofac J 44:149-154 (2007).
49.
Prado FB, Freire AR, Cláudia Rossi A, Ledogar JA, Smith AL, et al: Review of in vivo bone strain studies and finite element models of the zygomatic complex in humans and nonhuman primates: implications for clinical research and practice. Anat Rec (Hoboken) 299:1753-1778 (2016).
50.
Rayfield EJ: Finite element analysis and understanding the biomechanics and evolution of living and fossil organisms. Ann Rev Ear Plan Sci 35:541-576 (2007).
51.
Remmler D, Olson L, Ekstrom R, Duke D, Metamoros A, et al: Pre-surgical CT/FEA for craniofacial distraction: I. Methodology, development, and validation of the cranial finite element model. Med Eng Phys 20:607-619 (1998).
52.
Richtsmeier JT, Flaherty K: Hand in glove: brain and skull in development and dysmorphogenesis. Acta Neuropathol 125:469-489 (2013).
53.
Roth S, Raul JS, Willinger R: Finite element modelling of paediatric head impact: global validation against experimental data. Comput Methods Programs Biome 99:25-33 (2010).
54.
Scheuer L, Black S: The Juvenile Skeleton (Elsevier Academic Press, New York 2004).
55.
Simpson A, Wong AL, Bezuhly M: Surgical correction of nonsyndromic sagittal craniosynostosis concepts and controversies. Ann Plast Surg 78:103-110 (2017).
56.
Szwedowski TD, Fialkov J, Whyne CM: Sensitivity analysis of a validated subject-specific finite element model of the human craniofacial skeleton. Proc Inst Mech Eng H 225:58-67 (2011).
57.
Tanne K, Miyasaka J, Yamagata Y, Sachdeva R, Tsutsumi S, Sakuda M: Three-dimensional model of the human craniofacial skeleton: method and preliminary results using finite element analysis. J Biomed Eng 10:246-252 (1988).
58.
Taylor JA, Maugans TA: Comparison of spring-mediated cranioplasty to minimally invasive strip craniectomy and barrel staving for early treatment of sagittal craniosynostosis. J Craniofac Surg 22:1225-1229 (2011).
59.
Thomas GP, Johnson D, Byren JC, Jayamohan J, Magdum SA, et al: Long-term morphological outcomes in nonsyndromic sagittal craniosynostosis: a comparison of 2 techniques. J Craniofac Surg 26:19-25 (2015).
60.
Toro-Ibacache V, Fitton LC, Fagan MJ, O'Higgins P: Validity and sensitivity of a human cranial finite element model: implications for comparative studies of biting performance. J Anat 228:70-84 (2016).
61.
van der Meulen J, van der Hulst R, van Adrichem L, Arnaud E, Chin-Shong D, et al: The increase of metopic synostosis: a pan-European observation. J Craniofac Surg 20:283-286 (2009).
62.
Wang J, Zou D, Li Z, Huang P, Li D, et al: Mechanical properties of cranial bones and sutures in 1-2-year-old infants. Med Sci Monit 20:1808-1813 (2014).
63.
Wang JW, Huang J, Li ZD, Zou DH, Li Z, et al: Research progress on biomechanics of craniocerebral injury in children (in Chinese). Fa Yi Xue Za Zhi 32:448-431 (2016).
64.
Wang Q, Wright BW, Smith A, Chalk J, Byron CD: Mechanical impact of incisor loading on the primate midfacial skeleton and its relevance to human evolution. Anat Rec (Hoboken) 293:607-617 (2010).
65.
Weickenmeier J, Fischer C, Carter D, Kuhl E, Goriety A: Dimensional, geometrical, and physical constraints in skull growth. Phys Rev Lett 118:248101 (2017).
66.
Wilkie AOM, Johnson D, Wall SA: Clinical genetics of craniosynostosis. Curr Opin Pediatr 29:622-628 (2017).
67.
Wolański W, Larysz D, Gzik M, Kawlewska E: Modeling and biomechanical analysis of craniosynostosis correction with the use of finite element method. Int J Numer Method Biomed Eng 29:916-925 (2013).
68.
You J, Jiang X, Hu M, Wang N, Shen Z, et al: The bone slot effect study of PI procedure for craniosynostosis correction plan based on finite element method. 3rd International Conference on Biomedical Engineering and Informatics, Oct 16-18, Yantai, pp 605-608 (2010).
69.
Zhang G, Tan H, Qian X, Zhang J, Li K, et al: A systematic approach to predicting spring force for sagittal craniosynostosis surgery. J Craniofac Surg 27:636-643 (2016).
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2018
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