Skip to Main Content
Skip Nav Destination
 
 

Medical Principles and Practice


Guidelines

 

About the Journal

Aims and Scope

Medical Principles and Practice is an international, peer-reviewed, FREE (authors do not pay for publication) open-access journal that covers all areas of biomedical research. Medical Principles and Practice welcomes high-quality science that seeks to elucidate the molecular and cellular basis of normal and pathological biological processes and contributes substantially to advancement of knowledge. The focus of Medical Principles and Practice is on original research, reviews, and systematic reviews that provide novel and important mechanistic insights. Papers accepted for publication in Medical Principles and Practice can therefore fall under the umbrellas of not only medicine, but also biochemistry, biophysics, genetics and epigenetics, immunology, microbiology, molecular biology, pathology, pharmacology, physiology, systems biology, etc. Descriptive studies stating only facts and observations, without mechanistic evidence and insights, studies covering perceptions or attitudes, studies based on unverified questionnaires, and works of purely local interest are discouraged.

Article Types

Research Article

Research Articles report on primary research. They must describe significant and original observations. Consideration for publication is based on the article’s originality, novelty, and scientific soundness, and the appropriateness of its analysis.
Research Articles are reports of original work. Authors are asked to follow the EQUATOR Network for Research Articles.
Prior approval from an Institutional Review Board (IRB) or an Ethics Review Committee is required for all investigations involving human subjects.

A downloadable template is available below.

Documents

Research Article Clinical Investigations_MPP (DOCX, 40 KB)

Research Article Laboratory Investigations_MPP (DOCX, 40 KB)

DoubleBlind TitlePage ResearchArticle (DOCX, 25 KB)

Authors may submit the following types of Research Articles:

- Clinical Investigations
- Laboratory Investigations

Research Articles include laboratory and clinical investigations as well as research not previously published or being considered for publication elsewhere. A Research Article may describe new developments or strategies or innovative methods or novel results and is judged on the quality of its scientific content and contribution to existing knowledge.

Research Articles are limited to approximately 19 pages double-spaced using 12-point Times New Roman font, including a maximum of 30 references, and all tables and figures. The text should contain a Title page, Highlights, a structured Abstract of 250 words, an Introduction, Materials and Methods (laboratory investigations) or Subjects and Methods (clinical investigations), Results, a Discussion, a Conclusion, Acknowledgements (if any), References, Tables, Figure Legends, and Figures in this order.

Review Article

Review Articles are considered reviews of research or summary articles. They are state-of-the-art papers covering a current topic by experts in the field. They should give evidence on and provide answers to a well-defined aspect or question in a particular area. Review Articles must include a critical discussion of the reported data and give a clear conclusion with potential impacts on the standard of care.

A downloadable template is available below.

Documents

Review Article (DOCX, 35 KB)

DoubleBlind TitlePage ReviewArticle (DOCX, 27 KB)

Reviews are articles on research of current interest and are also subject to peer review. Reviews present and critically evaluate the current state of a field with illustrative examples from authoritative sources to convey an indication of trends and likely future developments and provide a list of important references in the current literature. A simple “review of the literature” is not acceptable.

Review Articles are limited to 35 pages including references, tables, and figures. There is no specified limit for the number of references. The abstract should be unstructured and with a maximum of 250 words.

Systematic Review

Systematic Reviews are literature reviews focused on a research question that synthesizes all high-quality research evidence relevant to that question. Systematic Reviews should be presented in the Introduction, Methods, Results, Discussion format. The subject must be clearly defined. The objective of a Systematic Review should be to arrive at an evidence-based conclusion. The Methods section should give a clear indication of the literature search strategy, data extraction procedure, grading of evidence, and kind of analysis used. We strongly encourage authors to comply with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

A downloadable template is available below.

Documents

Systematic Review Article (DOCX, 40 KB)

DoubleBlind TitlePage ReviewArticle (DOCX, 25 KB)

The abstract should be structured and with a maximum of 250 words.

Brief Report

Brief Reports are short and/or rapid announcements of research results. They must contain data derived from cutting-edge research and be of potential interest to a large proportion of the readership. They are independent, concise reports representing a significant contribution to the field. Such communications should represent complete, original studies and should be arranged in the same way as full-length manuscripts with subheadings.

A downloadable template is available below.

Documents

Brief Report (DOCX, 40 KB)

DoubleBlind TitlePage BriefReport (DOCX, 25 KB)

A Brief Report is an independent, concise report representing a significant contribution to health sciences. Brief Reports are used to report important preliminary original research findings that are novel or groundbreaking and need only demonstrate a “proof of principle.” Authors are encouraged to submit a Research Article following their Brief Report.

Brief Reports follow the structure of Research Articles but are limited to 6 manuscript pages (approximately 1,000 words), a structured abstract of 150 words and a maximum of 10 references and 1 table or figure.

Letter

Letters may explore subjects related to matters discussed in the journal, providing the author’s perspective on a subject. Letters may discuss a recently published article and may lend support or constructively critique the article in line with the author’s experience. The editors reserve the right to share such letters to the authors of the article concerned prior to publication in order to permit response, ideally in the same issue of the journal. Letters should not include original data.

 

A downloadable template is available below.

Documents

Letter (DOCX, 34 KB)

DoubleBlind TitlePage Letter (DOCX, 27 KB)

Please note that Medical Principles and Practice does not publish Case Reports.

Contact Information

Should you have any problems with your submission, please contact the editorial office:

Professor Raj Raghupathy

Editor-in-Chief
Medical Principles and Practice

Health Sciences Centre
Kuwait University
PO Box 24923
Safat 13110 (Kuwait)
Tel. +965 24636680/6670
MPP@hscm.ku.edu.kw

Editorial and Journal Policies

Getting Started

When preparing a manuscript, it is important to review the editorial policies. For full details, please visit the Publication Ethics and Editorial Policies page. Karger Publishers is a member of the Committee on Publication Ethics (COPE). Karger journals aim to adhere to the COPE Code of Conduct and Best Practice Guidelines.

The presentation of manuscripts should follow the Uniform Requirements for Manuscripts Submitted to Biomedical Journals from the International Committee of Medical Journal Editors (ICMJE). We recommend preparing the manuscript using the dedicated article template for the manuscript type.

Only papers written in English are considered. The articles should be comprehensible to a reader who is fluent in English and should be edited prior to submission to ensure that standard English grammar and usage are observed. Use of a professional language editing service prior to submission can help avoid delays with the review process.

Karger recommends the use of original images and materials whenever possible. If a submitted manuscript contains third-party copyright material(s), it is the authors’ sole responsibility to obtain permission from the relevant copyright holder for reusing the material(s), including any associated licensing fee. The copyright and usage information needs to be checked carefully to avoid copyright infringement. The author(s) is and will remain personally liable for any copyright infringements.

Most publishers offer a quick and easy way to clear permissions for their content via the built-in website application RightsLink or via https://www.copyright.com/get-permissions/. Another widely used licensing tool is PLSClear. Please check the publishers’ websites for the available options and user instructions.

The authors agree that their name, affiliation with their institution and contact details will be available to third parties after the article has been published. Those third parties may be placed within or outside of the European Economic Area.

Research and Publication Ethics

All submitted manuscripts must contain a statements section after the main body of the text, but before the reference list. For full details, please visit the Publication Ethics and Editorial Policies page.

Further Conditions

Early View

Accepted papers are published online in the unedited, original manuscript version within a few days of acceptance, subject to the authors accepting and confirming applicable conditions of publication, including publication charges. The Early View version will be replaced by the version of record once available.

Peer Review

Peer Review Policy

All Karger journals employ a rigorous peer-review process to confirm the validity and ensure scientific accuracy of published articles. Independent researchers with relevant expertise assess submitted manuscripts to help journal editors determine whether a manuscript should be published in their journal. All articles, except for Editorials and some Correspondence articles, are externally peer reviewed, typically by at least two individuals with expertise in the manuscript content area and/or research methods, before a final decision is made about acceptance for publication.


Peer Review Type and Process

Medical Principles and Practice uses a double-blind peer review system where the reviewers do not know the names of the authors, and the authors do not know who reviewed their manuscript. A list of all authors and their institutes and affiliations as well as up-to-date postal address of the corresponding author (complete with postal code, telephone number, and e-mail address) should be supplied as a separate document to ensure anonymous reviewing.

Please be aware that the Editorial Office does not edit manuscripts before sending them out for review, therefore you include author information or potentially identifiable information at your own risk and accept that this will be visible to reviewers.

For full details, including information about peer review policies and appeals process, please visit the Peer review – Karger Publishers page.

 

Article Preparation

Formatting

  • The preferred word processing program for manuscripts is Microsoft Word. Page and line numbering should be activated, and the level of subheadings should be indicated clearly.
  • Footnotes should be avoided. When essential, they should be numbered consecutively and appear at the foot of the appropriate page.
  • Abbreviations (with the exception of those clearly well established in the field) should be explained when they are first used both in the abstract and in the main text.
  • Units of measurement should be expressed in SI units wherever possible.
  • Generic names of drugs (first letter: lowercase) should be used whenever possible. Registered trade names (first letter: uppercase) should be marked with the superscript registration symbol ® or ™ when they are first mentioned.
  • The manuscript text, tables and figures must be submitted in separate files. Figure legends should be included at the end of manuscript text, not in the figure file. Table headers should be included above or below the table in the table file.

 

For full technical specifications, including those regarding tables, figures, and illustrations, please refer to Karger’s Technical Instructions to Publish a Paper.

Manuscript Arrangement

Title Page

The first page should contain a short and concise title plus a running head of no more than 80 characters. Abbreviations should be avoided.

Below the title, list all the authors’ names as outlined in the article sample, which can be downloaded under Article Types. Each listed author must have an affiliation, which comprises the department, university, or organization and its location, city, state/province (if applicable), and country.

Corresponding author information: Please supply the first and last name as well as an e-mail address at the bottom of the title page.

Keywords relevant to the article should be listed below the corresponding author information.

Body

Please refer to the Article Types section of the Guidelines for Authors for information on the relevant article structure, including maximum word counts and downloadable samples.

References

In-Text Citation

References in the text should be identified sequentially using Arabic numerals [in square brackets].

Reference List

The reference list should include only those publications which are cited in the text, arranged numerically in the order in which they are cited. Please number the reference list as shown below (i.e., without using full stops, brackets, etc.). The authors’ surnames should be followed by their initials with no punctuation other than a comma to separate individual authors. A maximum of 6 authors should be listed (followed by “et al.” if there are more than 6 authors). Material submitted for publication but not yet accepted should be referred to as “unpublished data” and should not be included in the reference list. Other pre-published or related materials with a DOI, e.g. preprint manuscripts, datasets, and code, may be included. More information on good referencing practice, as well as further examples, can be found in National Library of Medicine Style Guide for Authors.

Examples

Articles published in journals: 1 Sawant KV, Xu R, Cox R, Hawkins H, Sbrana E, Kolli D, et al. Chemokine CXCL1-mediated neutrophil trafficking in the lung: role of CXCR2 activation. J Innate Immun. 2015;6(7):647–58. (Journal names should be abbreviated according to the Index Medicus.)

Articles published only with DOI number: 2 Chen C, Hu Z. ApoE polymorphisms and the risk of different subtypes of stroke in the Chinese population: a comprehensive meta-analysis. Cerebrovasc Dis. DOI: 10.1159/000442678.

Monographs: 3 Matthews DE, Farewell VT. Using and understanding medical statistics. 5th ed, revised. Basel: Karger; 2015.

Edited Books: 4 Cohen SR, Gardner TW. Diabetic retinopathy and diabetic macular edema. In: Nguyen QD, Rodrigues EB, Farah ME, Mieler WF, Do DV, editors. Retinal pharmacotherapeutics. Dev Ophthalmol. Basel: Karger; 2016. Vol. 55; p. 137–46.

Websites: 5 Karger Publishers [Internet]. Basel: Transforming Vesalius: The 16th-Century Scientific Revolution Brought to Life for the 21st Century [cited 2013 Feb 4]. Available from: https://www.vesaliusfabrica.com/en/new-fabrica.html.

Figures and Tables

The figure legend should be placed at the end of the article, after the reference list. The figure legend should not be part of the figure file. Tables require a heading above or below the table in the table file. For more details please download the relevant article template from the section “Article Types”.

Online Supplementary Material

Online Supplementary Material may be used to enhance a publication and increase its visibility on the Web. Supplementary files (directly relevant but not essential to the conclusions of the paper) will undergo editorial review and should be submitted in a separate file with the original manuscript and with all subsequent submissions. The Editor(s) reserve(s) the right to limit the scope and length of supplementary material. Supplementary material must meet production quality standards for publication without the need for any modification or editing. For ease of reader access, we strongly recommend that files be less than 10 MB. Authors wishing to associate larger amounts of supplementary material with their article should deposit their data in an appropriate public data repository. Figures must have legends and tables require headings. All files must be named clearly. Acceptable files and formats are Word or PDF files, Excel spreadsheets (if the data cannot be converted properly into a PDF file), and multimedia files (MPEG, AVI, or QuickTime formats). All supplementary material should be referred to in the main text. A DOI number will be assigned to supplementary material, and it will be hosted online at https://karger.figshare.com under a CC BY license.

Author Services

Karger Publishers offer a range of services to assist authors with the preparation of their manuscript, including discounts for language editing services offered by third parties.

More information is available on the Author Resources section of the Karger homepage.

When submitting a manuscript, authors can add their ORCID number to their Karger account to ensure that their paper is accredited to them correctly.

Cost of Publication

Page Charges/Article Processing Charges

Article Processing Charges (APCs) are not levied in this journal.

Online Supplementary Material

We strongly encourage authors to make all the datasets on which the conclusions of the manuscript are based available. Online supplementary material is hosted for free with a published article. For ease of reader access, we strongly recommend that files be less than 10 MB. Authors wishing to associate larger amounts of supplementary material with their article should deposit their data in an appropriate public data repository.

Illustration Charges

Color illustrations are reproduced free of charge.

After Acceptance and Sharing Policies

Copyediting and Proofs

Manuscripts accepted for publication by Karger Publishers will undergo basic proofreading to check for obvious spelling and grammar mistakes. If you would prefer a more in-depth language editing service to improve clarity and style, please consult a service provider prior to submission. Please note that the use of a language editing service before submission is not a requirement for publication in the journal and does not guarantee that the manuscript will be considered for peer review or accepted.

Karger Publishers’ house style is based on internationally recognized standard manuals, including The Chicago Manual of Style.

Proof Central

An email containing a link to access the proofs will be sent to the contact author. The authors should check the document and respond to any questions that have been raised during copyediting within 48 hours. A provisional PDF can be viewed for an impression of the final layout of the manuscript.

Corrections to the text and tables should be made directly in the template. Changes to figures are discouraged but can be indicated with comments. Final layout and typesetting take place at a later stage.

Alterations made to proofs, other than the correction of errors introduced during production, are subject to review and may require editorial approval which could delay the publication of your manuscript

Please note that the revised proofs are not sent to the authors prior to typesetting and online publication unless there are exceptional circumstances. The article layout will be created according to the Karger standard.

DOI Number

A DOI number will be available as a unique identifier on the title page of each article. DOIs are useful for identifying and citing articles published online without volume or issue information (for more information, see www.doi.org).

Online First Publication

Licenses and Copyright

Articles published in Medical Principles and Practice are licensed under the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) license, unless otherwise agreed with Karger Publishers. When sharing or reusing any article, attribution must be given to the original source, using the statement "The final, published version of this article is available at http://karger.com/?doi=[insert DOI number]" (e.g., http://karger.com/?doi=10.1159/000365070). Reuse for commercial purposes requires permission from the publisher.

More information is available on the Karger website.

The copyright of the article is retained by the authors. The authors grant S. Karger AG, Basel, an exclusive unlimited license to publish the article under a Creative Commons license and identify S. Karger AG as the original publisher. Submission of a manuscript for publication implies the authors’ consent to publication under the applicable Creative Commons license and the terms and conditions of the Publisher’s Licensing Agreement.

Please note that metadata – essentially, data tags about article information such as authors and keywords that helps make articles discoverable by, for example, search engines – is governed by a separate policy. Refer to the FAQ on our Open Access web pages for details.

Archiving and Self-Archiving

All articles are archived in Portico. Articles may also be archived in PubMed Central if the journal is indexed there. Karger permits authors of Open Access articles to post the Version of Record (VOR) of their articles in Open Access repositories or on other websites. Preprints may be shared without restriction. Re-posted Open Access articles must follow the terms of the relevant Creative Commons license.

To ensure citations are credited to the Version of Record, Karger encourages authors to link to the published article on karger.com and include the following statement: "The Version of Record of this article is available at http://karger.com/?doi=[insert DOI number](e.g. http://karger.com/?doi=10.1159/000365070)."

Manuscripts to be archived in PubMed Central due to NIH funding requirements will be submitted by Karger on the authors’ behalf, as outlined under Funding Organizations.

Karger policies on Open Access, licensing and self-archiving can also be found at Sherpa Romeo.

Funding Organizations

If the authors are affiliated with an organization that has an Open Access agreement with Karger, the authors are prompted during submission to select from a list of these organizations. By choosing one of the listed organizations, eligibility can then be assessed.

NIH-Funded Research

The US National Institutes of Health (NIH) Public Access Policy mandates that the Author's Accepted Manuscript must be archived in its digital repository PubMed Central (PMC) within 12 months of the official publication date. As a service to authors, Karger Publishers submits the Version of Record of Open Access NIH-funded papers to PMC upon publication.

Plan S

To facilitate compliance with Coalition S/Plan S Open Access mandates, Karger publishes Plan S-funded Open Access articles with a CC BY license. Some Coalition S funders, such as Wellcome Trust, Bill & Melinda Gates Foundation and FWF, designate PMC as the repository in which to archive articles. Where PMC is the designated repository, Karger will deposit the Version of Record on the author’s behalf with the CC BY license. Authors should refer to their funders’ policies for details. Authors should check their funders’ requirements about how to declare their funding and any associated mandates within their manuscript.

Karger publishes some journals under the Transformative Journals model, compliant with Plan S. Find more information about Transformative Journals on the Karger website.

Other Funding Sources

Karger Publishers also complies with other funders’ requirements for submission to PMC. Authors should inform Karger about their grant providers during submission and include information on their grants in the Funding Sources section of their papers.

More information on funding sources can be found on the Karger website.

Submission

Cover Letter

In your cover letter, please describe the gap in knowledge that this manuscript addresses, and discuss the implications, significance and novelty of your research for the Editor. Furthermore, please emphasize the unique and important contributions that your manuscript makes to our understanding of the field. If your submission is part of a special issue of the journal, please refer to the specific name of the special issue in your cover letter and specify who invited the submission where appropriate.

Manuscript Submission

Manuscripts should be submitted online via the Medical Principles and Practice submission and peer review system by the manuscript’s corresponding author. The corresponding (submitting) author will automatically be the contact person for the manuscript for the peer review and production process. For fee payment and license signing, the contact author will be the first listed corresponding author.

The corresponding (submitting) author is solely responsible for managing all communication between the journal and all co-authors and acts on behalf of all listed authors. This ensures that all correspondence reaches a unique contact and thereby secures swift communication in particular throughout the submission, peer review and production process. Articles can be published with more than one corresponding author (usually limited to three), but only the submitting author can be accommodated during the submission, peer review and production process.

The corresponding (submitting) author’s specific responsibilities include:

  • Ensuring all the listed authors have approved the manuscript submission to the journal and agreed to all of the content including the author list, including the Submission Declaration
  • Handling the revision(s) and re-submission(s) of the manuscript until acceptance
  • After acceptance, manuscript proof reading and approving the final proof
  • Acting as the point of contact for queries about the published article. It is their responsibility to inform all co-authors of any matters arising in relation to the published article including questions relating to publication ethics, availability of data, materials, etc.

 

Where there are multiple corresponding authors, the first listed corresponding author’s specific responsibilities include:

  • Upon acceptance, ensuring that all listed authors agree to the license agreement
  • Arranging for payment of Page Charges/Article Processing Charges where required. The affiliation of the corresponding author will be used to determine eligibility for discounted or waived charges including discounted or waived APCs under read and publish/offsetting/OA agreements

 

Please note that the author names entered into the manuscript submission and peer review system should be identical to the information presented on the title page of the manuscript, including the sequence of authorship. The author names submitted should reflect the official publication names. It is the submitting (corresponding) author’s responsibility to ensure the accuracy of all content in the proof, including the names of co-authors, addresses and affiliations.

Before submission, please read the Submission Guidelines in full for specific requirements for manuscript preparation.

Submission Declaration

The submitting author will submit, on behalf of all authors, their manuscript for potential publication after full peer-review. All co-authors will confirm that the submitting author has authority to act on their behalf via the verification link sent out to all authors upon completion of the submission. Please refer to the Submission Declaration PDF for details.
Documents

Submission Declaration (PDF, 89 KB)


Close Modal

or Create an Account

Close Modal
Close Modal