Three brands of commercial honey were tested for their inhibitory effect on the growth of Helicobαcter pylori. H. pylori were isolated from gastric mucosa biopsy specimens using both pour plate and well inhibition zone techniques. At a concentration of 20% and above, all samples of honey were found to inhibit growth. This is the first report of the inhibitory effect of commercial honey on H. pylori. It may be of potential benefit in the treatment of peptic ulcer disease.