Objective: This study was designed to assess sexual dysfunction in women suffering from type 2 diabetes mellitus. Subjects and Methods: Forty-five type 2 diabetic, non-menopausal married women, aged 20-55 years, who were referred to Shahid Labbafinejad Clinics from March 2008 to June 2009 were included in this study. They were compared to 91 non-diabetic volunteers. Sexual function was evaluated by the sexual function questionnaire. Genitourinary examination was performed in all subjects. Blood sample tests were requested for fasting blood sugar, hemoglobin A1c, 2-hour postprandial glucose and lipid profile measurements. Ophthalmologic and neurologic examinations (checking deep tendon reflexes) were done for cases. Results: The mean age of cases and controls was 42.17± 5.91 and 34.96 ± 8.30 years, respectively (p < 0.001). The prevalence of a high probability of female sexual dysfunction in 6 domains including desire, arousal sensation, arousal lubrication, orgasm, pain and enjoyment was 71.1, 84.4, 55.6, 71.1, 8.9 and 66.7% in the diabetes mellitus women and 56.6, 67.0, 59.3, 57.1, 25.3 and 53.8% in the non-diabetic volunteers, respectively. Differences were statistically significant in the 3 domains of desire, arousal sensation and pain (p < 0.05). Deep tendon reflexes were normal in all and 12.5% showed diabetic retinopathy. Conclusions: Sexual dysfunction in cases as well as in controls was high; however, further studies with a higher number of patients are needed to confirm the results.

1.
World Health Organization: Defining sexual health: report of a technical consultation on sexual health. Geneva, WHO, 2002.
2.
Ellenberg M: Impotence in diabetes: the neurologic factor. Ann Intern Med 1971;75:213-219.
3.
Rubin A, Babbott D: Impotence and diabetes mellitus. J Am Med Assoc 1958;168:498-500.
4.
Klein R, Klein BE, Lee KE, Moss SE, Cruickshanks KJ: Prevalence of self-reported erectile dysfunction in people with long-term IDDM. Diabetes Care 1996;19:135-141.
5.
Rosen RC, Taylor JF, Leiblum SR, Bachmann GA: Prevalence of sexual dysfunction in women: results of a survey study of 329 women in an outpatient gynecological clinic. J Sex Marital Ther 1993;19:171-188.
6.
Laumann EO, Paik A, Rosen RC: Sexual dysfunction in the United States: prevalence and predictors. JAMA 1999;281:537-544.
7.
Goldmeier D, Judd A, Schroeder K: Prevalence of sexual dysfunction in new heterosexual attenders at a central London genitourinary medicine clinic in 1998. Sex Transm Infect 2000;76:208-209.
8.
Bhasin S, Enzlin P, Coviello A, Basson R: Sexual dysfunction in men and women with endocrine disorders. Lancet 2007;369:597-611.
9.
Shifren JL, Davis SR, Moreau M, et al: Testosterone patch for the treatment of hypoactive sexual desire disorder in naturally menopausal women: results from the INTIMATE NM1 study. Menopause 2006;13:770-779.
10.
Bump RC, Mattiasson A, Bo K, Brubaker LP, DeLancey JO, Klarskov P, Shull BL, Smith AR: The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. Am J Obstet Gynecol 1996;175:10-17.
11.
Salonia A, Munarriz RM, Naspro R, et al: Women's sexual dysfunction: a pathophysiological review. BJU Int 2004;93:1156-1164.
12.
Giraldi A, Kristensen E: Sexual dysfunction in women with diabetes mellitus. J Sex Res 2010;47:199-211.
13.
Education and treatment in human sexuality: the training of health professionals. Report of a WHO meeting. World Health Organ Tech Rep Ser 1975;572:5-33.
14.
Meeking DR, Fosbury JA, Cummings MH, et al: Sexual dysfunction and sexual health concerns in women with diabetes. Sex Dysfunct 1999;I:83-87.
15.
Fatemi SS, Taghavi SM: Evaluation of sexual function in women with type 2 diabetes mellitus. Diab Vasc Dis Res 2009;6:38-39.
16.
Schreiner-Engel P, Schiavi RC, Vietorisz D, De Simone Eichel J, Smith H: Diabetes and female sexuality: a comparative study of women in relationships. J Sex Marital Ther 1985;11:165-175.
17.
Safarinejad MR: Female sexual dysfunction in a population-based study in Iran: prevalence and associated risk factors. Int J Impot Res 2006;18:382-395.
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