The condition of hepatitis B surface antigen (HBsAg) persistent antigenaemia was studied in 96 cases of hepatosplenic schistosomiasis and 110 control patients admitted to Cairo University Hospital. The aim was to determine the incidence of HBsAg carriers among hepatosplenic schistosomiasis cases. The enzyme-linked immunosorbent assay (ELISA) technique was used to detect HBsAg in serum samples. A total of 15.6% of patients with hepatosplenic schistosomiasis were seropositive compared with only 1.8% of the control group. Five patients out of 16 who had to be operated on for bleeding varices were seropositive for HBsAg. This high figure indicates the need to consider precautions for the safety of personnel operating on chronic bilharziasis patients. In addition, in cases of hepatosplenic schistosomiasis associated with HBS persistent antigenaemia, liver derangement and chronic active hepatitis must be anticipated and their clinical and laboratory manifestations looked for.

Keywords:
Hepatitis B, Schistosomiasis, Antigens, surface, Suppressor factors, immunologic, Hepatitis, chronic active
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© 1990 S. Karger AG, Basel
1990
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