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Keywords: Working memory
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Journal Articles
Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles
FreeThomas D. Prevot, Guanguan Li, Aleksandra Vidojevic, Keith A. Misquitta, Corey Fee, Anja Santrac, Daniel E. Knutson, Michael Rajesh Stephen, Revathi Kodali, Nicolas M. Zahn, Leggy A. Arnold, Petra Scholze, Janet L. Fisher, Bojan D. Marković, Mounira Banasr, James M. Cook, Miroslav Savic, Etienne Sibille
Journal:
Molecular Neuropsychiatry
Molecular Neuropsychiatry (2019) 5 (2): 84–97.
Published Online: 23 January 2019
... for positive allosteric modulation at multiple α-GABAA-R (α-positive allosteric modulators), pharmacokinetic properties, as well as anxiolytic and antidepressant activities in adult mice. Efficacy at reversing stress-induced or age-related working memory deficits was assessed using a spontaneous alternation...
