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Keywords: Gamma-aminobutyric acid
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Journal Articles

Cell Type-Specific Gene Expression of Alpha 5 Subunit-Containing Gamma-Aminobutyric Acid Subtype A Receptors in Human and Mouse Frontal Cortex

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Subject Area:
Further Areas , Genetics , Neurology and Neuroscience , Psychiatry and Psychology
Xiyue Hu, Brad R. Rocco, Corey Fee, Etienne Sibille
Journal: Molecular Neuropsychiatry
Molecular Neuropsychiatry (2019) 4 (4): 204–215.
https://doi.org/10.1159/000495840
Published Online: 23 January 2019
... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Gamma-aminobutyric acid GABRA5 Cortical microcircuitry Somatostatin Fluorescence in situ hybridization Multiple brain functions, from sensory processing to cognitive...
View articletitled, Cell Type-Specific Gene Expression of Alpha 5 Subunit-Containing Gamma-Aminobutyric Acid Subtype A Receptors in Human and Mouse Frontal Cortex
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Journal Articles

Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles

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Subject Area:
Further Areas , Genetics , Neurology and Neuroscience , Psychiatry and Psychology
Thomas D. Prevot, Guanguan Li, Aleksandra Vidojevic, Keith A. Misquitta, Corey Fee, Anja Santrac, Daniel E. Knutson, Michael Rajesh Stephen, Revathi Kodali, Nicolas M. Zahn, Leggy A. Arnold, Petra Scholze, Janet L. Fisher, Bojan D. Marković, Mounira Banasr, James M. Cook, Miroslav Savic, Etienne Sibille
Journal: Molecular Neuropsychiatry
Molecular Neuropsychiatry (2019) 5 (2): 84–97.
https://doi.org/10.1159/000496086
Published Online: 23 January 2019
... Sibille Altered gamma-aminobutyric acid (GABA) function is consistently reported in psychiatric disorders, normal aging, and neurodegenerative disorders and reduced function of GABA interneurons is associated with both mood and cognitive symptoms. Benzodiazepines (BZ) have broad anxiolytic, but also...
View articletitled, Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles
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Journal Articles

Ketamine’s Effects on the Glutamatergic and GABAergic Systems: A Proteomics and Metabolomics Study in Mice

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Subject Area:
Further Areas , Genetics , Neurology and Neuroscience , Psychiatry and Psychology
Katja Weckmann, Michael J. Deery, Julie A. Howard, Renata Feret, John M. Asara, Frederik Dethloff, Michaela D. Filiou, Christiana Labermaier, Giuseppina Maccarrone, Kathryn S. Lilley, Marianne Mueller, Christoph W. Turck
Journal: Molecular Neuropsychiatry
Molecular Neuropsychiatry (2019) 5 (1): 42–51.
https://doi.org/10.1159/000493425
Published Online: 15 November 2018
... labeling proteome comparison of ketamine- and vehicle-treated mice. The metabolomics and proteomics datasets were used to further elucidate ketamine’s mode of action on the gamma-aminobutyric acid (GABA)ergic and glutamatergic systems. In addition, myelin basic protein levels were analyzed by Western Blot...
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