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Keywords: Clozapine
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Journal Articles
Pharmacogenetic Analysis of Functional Glutamate System Gene Variants and Clinical Response to Clozapine
Available to PurchaseDanielle L. Taylor, Arun K. Tiwari, Jeffrey A. Lieberman, Steven G. Potkin, Herbert Y. Meltzer, Joanne Knight, Gary Remington, Daniel J. Müller, James L. Kennedy
Journal:
Molecular Neuropsychiatry
Molecular Neuropsychiatry (2017) 2 (4): 185–197.
Published Online: 12 October 2016
... to clozapine (CLZ), which is the drug of choice for treatment-resistant SCZ. Response to antipsychotic therapy is highly variable, although twin studies suggest a genetic component. We investigated the association of 10 glutamate system gene variants with CLZ response using standard genotyping procedures. GRM2...