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Keywords: Anxiety
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Journal Articles

Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles

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Subject Area:
Further Areas , Genetics , Neurology and Neuroscience , Psychiatry and Psychology
Thomas D. Prevot, Guanguan Li, Aleksandra Vidojevic, Keith A. Misquitta, Corey Fee, Anja Santrac, Daniel E. Knutson, Michael Rajesh Stephen, Revathi Kodali, Nicolas M. Zahn, Leggy A. Arnold, Petra Scholze, Janet L. Fisher, Bojan D. Marković, Mounira Banasr, James M. Cook, Miroslav Savic, Etienne Sibille
Journal: Molecular Neuropsychiatry
Molecular Neuropsychiatry (2019) 5 (2): 84–97.
https://doi.org/10.1159/000496086
Published Online: 23 January 2019
... www.karger.com/doi/10.1159/000496086 for all online suppl. material). Using tests assessing anxiety- [ 28 ] and depressive- [ 29 ] like behaviors as well as working memory [ 30 ] in mice, we tested the hypothesis that novel IBZD-like ligands maintain the anxiolytic efficacies of BZs and display...
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Journal Articles

Clinical Utility of Combinatorial Pharmacogenomics-Guided Antidepressant Therapy: Evidence from Three Clinical Studies

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Subject Area:
Further Areas , Genetics , Neurology and Neuroscience , Psychiatry and Psychology
C. Anthony Altar, Joseph Carhart, Josiah D. Allen, Daniel Hall-Flavin, Joel Winner, Bryan Dechairo
Journal: Molecular Neuropsychiatry
Molecular Neuropsychiatry (2015) 1 (3): 145–155.
https://doi.org/10.1159/000430915
Published Online: 31 July 2015
... (p = 0.0002), a 1.7-fold relative improvement in response (p = 0.01), and a number needed to treat for one clinical response above that seen in the TAU group of 6.07. Depression Anxiety Translational medicine Genomics Polymorphism Allele Psychiatry Combinatorial pharmacogenomics...
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