... Ssk22p activates Hog1p. This activated form of Hog1p triggers osmotic stress response, impairs cell fusion and co-activates CWI gene expression. Thus, we place Ssk22p as a bridge between the PKC and HOG pathways. Despite this connection, Ssk22p might play an auxiliary role in the global response to acid...

... one molecular mechanism: double-strand break (DSB)-dependent stress-induced mutagenesis described in starving Escherichia coli . In it, the otherwise high-fidelity process of DSB repair by homologous recombination is switched to an error-prone mode under the control of the RpoS general stress response...