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Keywords: Diabetes
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Journal Articles
Subject Area:
Nephrology
Mineral and Electrolyte Metabolism (1999) 25 (4-6): 220–223.
Published Online: 13 February 2000
...James Bailey; Xiaonan Wang; S. Price In uremia, accelerated muscle protein degradation results from activation of the ATP-ubiquitin proteasome proteolytic pathway. Like uremia, other conditions (e.g., acidosis and diabetes) activate this pathway in rat muscles and are associated with excess...
Journal Articles
Subject Area:
Nephrology
Mineral and Electrolyte Metabolism (1998) 24 (6): 406–411.
Published Online: 11 January 1999
...Sharon Anderson Clinical, experimental, biochemical, and molecular biologic studies all invoke an important role for the renin-angiotensin system (RAS) in the pathogenesis of diabetic complications. Studies of pharmacologic interruption of the RAS with angiotensin-converting enzyme (ACE) inhibition...
Journal Articles
Journal Articles
Subject Area:
Nephrology
Mineral and Electrolyte Metabolism (1998) 24 (6): 438–445.
Published Online: 11 January 1999
...Matthew Weir Patients with hypertension and diabetes are frequently salt-sensitive. Consequently, increasing dietary salt intake results in a rise in systemic arterial pressure and an increase in proteinuria, as well as a progressive risk for developing renal injury. A difference in the renal...
Journal Articles
Subject Area:
Nephrology
Mineral and Electrolyte Metabolism (1998) 24 (6): 371–380.
Published Online: 11 January 1999
...Michael Brands; Joey Granger A principal, and unique, renal effector site for angiotensin II (ANG II) is the efferent arteriole, and that has generated considerable interest regarding potential benefits of ANG II inhibition in the treatment and prevention of diabetic renal injury. A hallmark...
Journal Articles
Subject Area:
Nephrology
Mineral and Electrolyte Metabolism (1998) 24 (6): 381–388.
Published Online: 11 January 1999
...Ton Rabelink; George Bakris In recent years endothelial function has been forwarded a modulator in the pathogenesis of diabetic nephropathy. This review summarizes how an imbalance between endothelium-derived reactive nitrogen species and reactive oxygen species as well as increased expression...
Journal Articles
Subject Area:
Nephrology
Mineral and Electrolyte Metabolism (1998) 24 (6): 412–422.
Published Online: 11 January 1999
...John Flack; Marwan Hamaty; Beth Staffileno Diabetes mellitus is associated with an inordinately high risk of virtually all manifestations of cardiovascular-renal disease including atherosclerotic coronary and peripheral vascular disease, congestive heart failure, stroke, nephropathy...
Journal Articles
Subject Area:
Nephrology
Mineral and Electrolyte Metabolism (1998) 24 (6): 389–399.
Published Online: 11 January 1999
.... Components of the amylin system (AS) have been shown to influence the activity of components of the renin-angiotensin system (RAS), and vice versa, in normal, hypertensive and diabetic models. For instance, amylin injected into humans and rats elicits a rapid rise in plasma renin activity. Furthermore...
Journal Articles
Subject Area:
Nephrology
Mineral and Electrolyte Metabolism (1998) 24 (1): 41–46.
Published Online: 05 November 1997
...Pietro Castellino; Mauro Giordano; Emanuela de Pascale; Anna Solini In poorly controlled diabetics, the whole-body protein flux is increased by 20–30% in comparison to well-controlled type I diabetes (IDDM) and normal subjects. Intensive insulin administration completely reverses...