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Keywords: DNA methylation
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Journal Articles
Medical Epigenetics (2016) 4 (1): 1–19.
Published Online: 24 March 2016
... or advertisements. GABA GABAergic neurotransmission Neurological disorders DNA methylation Histone modification γ-Aminobutyric acid (GABA) is a nonprotein amino acid that is a major inhibitory neurotransmitter for fast synaptic transmission in the adult brain. It is also fairly abundant...
Journal Articles
Medical Epigenetics (2014) 2 (2): 71–79.
Published Online: 11 June 2014
... have been associated with the neurodevelopment of healthy newborns quantified through the Neonatal Intensive Care Unit Network Neurobehavioral Scales (NNNS). Associations have been observed for DNA methylation of genes involved in cortisol (NR3C1, HSD11B) , serotonin (HTR2A) , and metabolic (LEP...
Journal Articles
Medical Epigenetics (2014) 2 (1): 53–59.
Published Online: 23 April 2014
...Monica D. Nye; Rebecca C. Fry; Cathrine Hoyo; Susan K. Murphy Increasing evidence suggests that epigenetic alterations can have a great impact on human health, and that epigenetic mechanisms (DNA methylation, histone modifications, and microRNAs) may be particularly relevant in responding...
Journal Articles
Medical Epigenetics (2014) 2 (1): 37–52.
Published Online: 25 March 2014
... expression that do not involve changes in the DNA sequence per se, represents the missing link. The nuclear-based mechanisms that contribute to epigenetic gene regulation can be broadly separated into three unique but highly interrelated processes, namely DNA methylation and hydroxymethylation, histone...
Journal Articles
Medical Epigenetics (2014) 2 (1): 28–36.
Published Online: 14 February 2014
...Benedetta Izzi; Alexandra M. Binder; Karin B. Michels Introduction: Bisulfite treatment of DNA introduces methylation-dependent sequence changes through selective chemical conversion of nonmethylated cytosine to uracil and serves as pretreatment step for the majority of DNA methylation analysis...
Journal Articles
Medical Epigenetics (2014) 2 (1): 20–27.
Published Online: 12 February 2014
..., instructions or products referred to in the content or advertisements. Epigenetics DNA methylation Developmental origins of health and disease Early life environment Non-communicable diseases (NCD) such as diabetes, cardiovascular disease (CVD) and the metabolic syndrome, account for over...
Journal Articles
Medical Epigenetics (2013) 1 (1): 37–45.
Published Online: 27 August 2013
... was implicated in the establishment of the epigenetic field defect, manifesting as aberrant DNA methylation [ 34 ]. Because epigenetic alterations are reversible, Ushijima and Hattori [ 34 ] argued that epigenetic drugs and anti-inflammatory drugs may be useful for the epigenetic prevention of gastric cancer...