... or advertisements. GABA GABAergic neurotransmission Neurological disorders DNA methylation Histone modification γ-Aminobutyric acid (GABA) is a nonprotein amino acid that is a major inhibitory neurotransmitter for fast synaptic transmission in the adult brain. It is also fairly abundant...

... have been associated with the neurodevelopment of healthy newborns quantified through the Neonatal Intensive Care Unit Network Neurobehavioral Scales (NNNS). Associations have been observed for DNA methylation of genes involved in cortisol (NR3C1, HSD11B) , serotonin (HTR2A) , and metabolic (LEP...

...Monica D. Nye; Rebecca C. Fry; Cathrine Hoyo; Susan K. Murphy Increasing evidence suggests that epigenetic alterations can have a great impact on human health, and that epigenetic mechanisms (DNA methylation, histone modifications, and microRNAs) may be particularly relevant in responding...

... expression that do not involve changes in the DNA sequence per se, represents the missing link. The nuclear-based mechanisms that contribute to epigenetic gene regulation can be broadly separated into three unique but highly interrelated processes, namely DNA methylation and hydroxymethylation, histone...

...Benedetta Izzi; Alexandra M. Binder; Karin B. Michels Introduction: Bisulfite treatment of DNA introduces methylation-dependent sequence changes through selective chemical conversion of nonmethylated cytosine to uracil and serves as pretreatment step for the majority of DNA methylation analysis...

..., instructions or products referred to in the content or advertisements. Epigenetics DNA methylation Developmental origins of health and disease Early life environment In humans, studies on the Dutch Hunger Winter cohort showed that periconceptual exposure to famine was associated with a small...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Patho-epigenetics Epigenetic regulation DNA methylation Polycomb...