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Keywords: Cytochrome P450
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Journal Articles
Journal:
Medical Cannabis and Cannabinoids
Med Cannabis Cannabinoids (2020) 3 (1): 61–73.
Published Online: 07 July 2020
.... These medications are said to have a Narrow Therapeutic Index (NTI). Most xenobiotic medications are metabolized by a phase I hepatic cytochrome P450 enzyme (oxidative/functionalization reaction) and then by a phase II conjugation reaction catalyzed by a hepatic UDP-glucurono-syltransferase (UGT) enzyme [ 19...
