.... Summary: Natural and synthetic derivatives of cannabis plants have been studied in the treatment of glaucoma since the 1970s. This review describes the potential mechanisms of the cannabinoids in the treatment of glaucoma, summarizes the findings of clinical studies describing the efficacy...

...Paul T. Kocis; Daniel J. Mallinson; Timothy J. Servinsky Jr. Introduction: With the continued societal and policy interest in cannabinoids, the Penn State Harrisburg Center for Survey Research (CSR) conducted a web survey (Cannabinoid Lion Poll) for adult-aged Pennsylvanians between March 6...

...Nimrod Brikenstein; Matan Birenboim; David Kenigsbuch; Jakob A. Shimshoni Introduction: Cannabis sativa L. inflorescences are widely used in the medicinal field as treatments for a variety of symptoms and illnesses due to their unique phytochemicals such as cannabinoids and terpenes. Common...

... excitatory glutamatergic and inhibitory γ-aminobutyric acid (GABA)-ergic signalling, substantial evidence implicates muscarinic receptors in the regulation of neural excitability. Summary: Cannabinoids have shown to reduce seizure activity and neuronal excitability in several epileptic models through...

..., instructions or products referred to in the content or advertisements. 2024 Cannabinoids Cannabis Gelatin Mannitol Marijuana Cannabis (marijuana) ( Cannabis sativa L. subsp. indica ) is a plant belonging to the Cannabaceae family. The presence of approximately 540 compounds has been...

... and an anti-inflammatory gene expression signature in people living with HIV, cannabinoids in combination with terpenes to overcome cancer resistance, and health and behavioral consequences of perinatal cannabidiol exposure in mice raised to adulthood. Other abstracts explored topics such as the impact...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Medical cannabis Neuropathic pain Cannabinoids Sleep disturbance Side effect Neuropathic pain has its origin in lesions or diseases affecting the central...

... ethanol as solvent, followed by overnight decarboxylation in a reflux condenser system. The extracts were characterized for their cannabinoid content using NMR and HPLC-PDA-ELSD-ESIMS. CYP inhibition studies with the cannabis extracts and pure cannabinoids (tetrahydrocannabinol [THC] and cannabidiol [CBD...

... marijuana Cannabis Cannabinoids Cannabidiol Marijuana efficacy Marijuana clinical outcomes Currently, some form of cannabis is legal in all but three states in the USA [1]. Florida approved cannabis, referred to as medical marijuana in the state legislation, for persons with qualifying...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Marijuana Cannabis Cannabinoids Cardiovascular effects Major adverse cardiovascular events Drug-drug interactions The American Heart Association (AHA...

...Manikandan Palrasu; Lillianne Wright; Manish Patel; Lindsey Leech; Scotty Branch; Shea Harrelson; Saeed Khan Cannabis and its natural derivatives have emerged as promising therapeutics for multiple pathological and nonpathological medical conditions. For example, cannabinoids, the most popular...

... and BChE can lead to cholinergic deficiency, which is associated with several neurological disorders including cognitive decline and memory impairments. Preclinical studies support that some cannabinoids including cannabidiol (CBD) and tetrahydrocannabinol (THC) may exert pharmacological effects...

...Sarah Abelev; Leon N. Warne; Melissa Benson; Mark Hardy; Sunny Nayee; John Barlow Introduction: Medicinal cannabis is prescribed in Australia for patients with chronic refractory pain conditions. However, measures of safety and effectiveness of different cannabinoids are lacking. We designed...

... of an oromucosal cannabinoid spray (AP701) containing a lipid-based nanoparticular drug formulation standardized to ∆-9-tetrahydrocannabinol (THC). Methods: Twelve healthy male subjects received a single dose of AP701 (12 sprays) containing 3.96 mg THC. Plasma samples were drawn 10 min–30 h post dose for analysis...

..., a growing number of animal and human studies have been undertaken to evaluate the impact of cannabis and cannabinoid signaling elements on the natural history of IBD and its associated complications. There is little clinical evidence supporting the ability of cannabis or related products to treat the GI...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Medical marijuana Cannabis Cannabinoids Cannabidiol Marijuana efficacy Commonly recommended conditions for marijuana...

...Myriam El Biali; Barbara Broers; Marie Besson; Jules Demeules Since the endocannabinoid system is involved in immune function, the effect of cannabinoid intake on infectious conditions is questioned for several years and is of particular interest in the COVID 19 pandemia. Some data suggest...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cannabinoids Cannabidiol Emergencies Overdose Synthetic cannabinoids Preclinical Science and Clinical Studies...

...Barbara Broers; Zacharie Patà; Aline Mina; James Wampfler; Christian de Saussure; Sophie Pautex Background: Dementia is increasing worldwide. No effective medication is currently available for the treatment of the underlying disease and accompanying behavioral symptoms. Cannabinoids might have...

...Carina Hasenoehrl; David Feuersinger; Melanie Kienzl; Rudolf Schicho The cannabinoid-responsive G protein-coupled receptor GPR55 and its endogenous ligand L-α-lysophosphatidyl-inositol (LPI) have been reported to play a role in several cancers. A proliferation-enhancing effect of GPR55 has been...