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Keywords: DNA methylation
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Journal Articles
Journal:
Liver Cancer
Liver Cancer (2014) 3 (3-4): 417–427.
Published Online: 08 August 2014
... genes (TSGs) in HCC, and this hypermethylation may promote carcinogenesis through the transcriptional inactivation of downstream TSGs. The DNA damage induced by oxidation is a trigger of abnormal DNA methylation and inactivation of TSGs through recruitment of the polycomb repressive complex...
