...Amit G. Singal; Jagpreet Chhatwal; Neehar Parikh; Elliot Tapper Introduction: Given suboptimal performance of ultrasound-based surveillance for early hepatocellular carcinoma (HCC) detection in patients with cirrhosis, there is interest in alternative surveillance strategies, including blood-based...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Survival Benefit Cirrhosis Systemic treatment About one-third...

... bodyweight was ≥60 kg or 8 mg if baseline bodyweight was <60 kg, given once daily orally) [ 3 ]. HCC was staged according to BCLC staging system, and cirrhosis was graded according to the Child-Pugh classification [ 12, 13 ]. Neoplastic portal vein thrombosis (nPVT) was defined at baseline CT scan...

... score (PS) matching in 1:2 ratio of covariates including baseline characteristics, causes of cirrhosis, Child-Pugh status, prior HCC treatment, comorbidities, concurrent medications, and laboratory results including alpha fetoprotein. Results: A total of 395 HCC patients who had received ICIs were...

... to the effects of the COVID-19 pandemic because the hepatic injury (discussed further below) caused by SARS-CoV-2 could complicate the existing hepatitis virus infection and cirrhosis in most HCC patients. Furthermore, management of HCC relies heavily on multidisciplinary approaches involving hepatobiliary...

... Cirrhosis Primary liver cancer was the sixth most common malignancy worldwide in 2018, and hepatocellular carcinoma (HCC) accounts for 75–85% of primary liver cancer [ 1 ], with an increasing incidence in Europe and the USA [ 2 ]. The prognosis of patients with HCC is quite poor, with a reported 5...

... score (PS) calibration of Cox regression estimates to adjust for unmeasured confounding. Results: We included 22,787 patients, of whom 96.5% had cirrhosis. In the unadjusted analysis, non-cirrhotic patients had an increased risk of overall mortality with a hazard ratio (HR) of 1.37 (95% confidence...

... and may promote metastasis. Traditionally, thrombocytopenia, a hallmark of cirrhosis, was associated with hepatocellular carcinoma (HCC) development. However, the impact of platelet count on outcome in patients with established HCC is not well studied. Methods: Outcomes of patients with cirrhosis...

... conferences where experts worked up guidelines to standardize this approach and improve its safety. However, most laparoscopic hepatectomies were performed in patients with liver metastases. The concurrent presence of liver cirrhosis with hepatocellular carcinoma (HCC) poses a great challenge to clinicians...

... worldwide, and a rising cause of cancer mortality in the U.S. Liver cirrhosis is the major risk factor for HCC. Surveillance of persons with cirrhosis facilitates early detection and improves outcomes. We assessed the surveillance rate for HCC within a major academic health system and identified factors...

..., and the evaluation of response to antiangiogenic treatment using dedicated software. Cholangiocarcinoma Cirrhosis Diagnosis Hepatocellular carcinoma Treatment Ultrasonography (US) has substantially impacted the way to manage liver cancer since its introduction in the 1980's. In particular the arrival...

..., Peck-Radosavljevic M: Sorafenib in unresectable hepatocellular carcinoma from mild to advanced stage liver cirrhosis. Oncologist 2009;14:70-76. 15. Marrero JA, Lencioni R, Ye SL, Kudo M, Bronowicki JP, Chen XP, et al: Final analysis of GIDEON (Global Investigation of Therapeutic Decisions...

... in the HCC patients. Cirrhosis is almost always present when HCC is diagnosed. Dietary iron overload is a condition which occurs in rural-dwelling Black Africans in southern Africa as a result of the consumption, over time, of large volumes of alcohol home-brewed in iron containers and having...

...Gayatri Ramakrishna; Archana Rastogi; Nirupama Trehanpati; Bijoya Sen; Ritu Khosla; Shiv K. Sarin Sequential progression from chronic liver disease to fibrosis and to cirrhosis culminates in neoplasia in hepatocellular carcinoma (HCC). The preneoplastic setting of the cirrhotic background provides...

... owing to the high propensity of HCC to invade the portal vein branches and the underlying liver cirrhosis, which is the ideal background for HCC development. Two pivotal surgical techniques are commonly used to reduce such recurrences: anatomical resection (AR) and achievement of negative margins...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cirrhosis Hepatocellular Carcinoma Liver resection Liver transplantation Recurrence Review Liver Cancer 2012;1:71 82 DOI: 10.1159/000342403...