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Atsushi Hiraoka
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Journal Articles

Disease Etiology Impact on Outcomes of Hepatocellular Carcinoma Patients Treated with Atezolizumab plus Bevacizumab: A Real-World, Multicenter Study

Subject Area:
Gastroenterology , Oncology
Federico Rossari, Toshifumi Tada, Goki Suda, Shigeo Shimose, Masatoshi Kudo, Changhoon Yoo, Jaekyung Cheon, Fabian Finkelmeier, Ho Yeong Lim, José Presa, Gianluca Masi, Francesca Bergamo, Elisabeth Amadeo, Francesco Vitiello, Takashi Kumada, Naoya Sakamoto, Hideki Iwamoto, Tomoko Aoki, Hong Jae Chon, Vera Himmelsbach, Massimo Iavarone, Giuseppe Cabibbo, Margarida Montes, Francesco Giuseppe Foschi, Caterina Vivaldi, Caterina Soldà, Takuya Sho, Takashi Niizeki, Naoshi Nishida, Christoph Steup, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi, Shinya Fukunishi, Kunihiko Tsuji, Toru Ishikawa, Kazuto Tajiri, Hironori Ochi, Satoshi Yasuda, Hidenori Toyoda, Chikara Ogawa, Takashi Nishimura, Takeshi Hatanaka, Satoru Kakizaki, Noritomo Shimada, Kazuhito Kawata, Atsushi Hiraoka, Fujimasa Tada, Hideko Ohama, Kazuhiro Nouso, Asahiro Morishita, Akemi Tsutsui, Takuya Nagano, Norio Itokawa, Tomomi Okubo, Michitaka Imai, Hisashi Kosaka, Atsushi Naganuma, Yohei Koizumi, Shinichiro Nakamura, Masaaki Kaibori, Hiroko Iijima, Yoichi Hiasa, Mara Persano, Silvia Foti, Silvia Camera, Bernardo Stefanini, Mario Scartozzi, Stefano Cascinu, Andrea Casadei-Gardini, Margherita Rimini
Journal: Liver Cancer
Liver Cancer (2024) 13 (5): 522–536.
https://doi.org/10.1159/000537915
Published Online: 10 April 2024
View article titled, Disease Etiology Impact on Outcomes of Hepatocellular Carcinoma Patients Treated with Atezolizumab plus Bevacizumab: A Real-World, Multicenter Study
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Journal Articles

Letter regarding “Impact of Bevacizumab Being Skipped due to Adverse Events of Special Interest for Bevacizumab in Patients with Unresectable Hepatocellular Carcinoma Treated with Atezolizumab plus Bevacizumab: An Exploratory Analysis of the Phase III IMbrave150 Study”

Subject Area:
Gastroenterology , Oncology
Takeshi Hatanaka, Atsushi Hiraoka, Toshifumi Tada, Satoru Kakizaki
Journal: Liver Cancer
Liver Cancer (2024) 13 (6): 669–670.
https://doi.org/10.1159/000538580
Published Online: 27 March 2024
View article titled, Letter regarding “Impact of Bevacizumab Being Skipped due to Adverse Events of Special Interest for Bevacizumab in Patients with Unresectable Hepatocellular Carcinoma Treated with Atezolizumab plus Bevacizumab: An Exploratory Analysis of the Phase III IMbrave150 Study”
Open the PDF for Letter regarding “Impact of Bevacizumab Being Skipped due to Adverse Events of Special Interest for Bevacizumab in Patients with Unresectable Hepatocellular Carcinoma Treated with Atezolizumab plus Bevacizumab: An Exploratory Analysis of the Phase III IMbrave150 Study” in another window
Journal Articles

Incidence and Predictors of Esophagogastric Varices Bleeding in Patients with Hepatocellular Carcinoma in Lenvatinib

Subject Area:
Gastroenterology , Oncology
Massimo Iavarone, Eleonora Alimenti, Toshifumi Tada, Shigeo Shimose, Goki Suda, Changhoon Yoo, Caterina Soldà, Fabio Piscaglia, Giulia Tosetti, Fabio Marra, Caterina Vivaldi, Fabio Conti, Marta Schirripa, Hideki Iwamoto, Takuya Sho, So Heun Lee, Mario Domenico Rizzato, Matteo Tonnini, Margherita Rimini, Claudia Campani, Gianluca Masi, Francesco Foschi, Mariangela Bruccoleri, Takumi Kawaguchi, Takashi Kumada, Atsushi Hiraoka, Masanori Atsukawa, Shinya Fukunishi, Toru Ishikawa, Kazuto Tajiri, Hironori Ochi, Satoshi Yasuda, Hidenori Toyoda, Takeshi Hatanaka, Satoru Kakizaki, Kazuhito Kawata, Fujimasa Tada, Hideko Ohama, Norio Itokawa, Tomomi Okubo, Taeang Arai, Michitaka Imai, Atsushi Naganuma, Andrea Casadei-Gardini, Pietro Lampertico
Journal: Liver Cancer
Liver Cancer (2024) 13 (2): 215–226.
https://doi.org/10.1159/000534127
Published Online: 14 September 2023
View article titled, Incidence and Predictors of Esophagogastric Varices Bleeding in Patients with Hepatocellular Carcinoma in Lenvatinib
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Journal Articles

Multicenter Phase II Trial of Lenvatinib plus Hepatic Intra-Arterial Infusion Chemotherapy with Cisplatin for Advanced Hepatocellular Carcinoma: LEOPARD

Subject Area:
Gastroenterology , Oncology
Masafumi Ikeda, Tatsuya Yamashita, Sadahisa Ogasawara, Masatoshi Kudo, Yoshitaka Inaba, Manabu Morimoto, Kaoru Tsuchiya, Satoshi Shimizu, Yasushi Kojima, Atsushi Hiraoka, Kazuhiro Nouso, Hiroshi Aikata, Kazushi Numata, Tosiya Sato, Takuji Okusaka, Junji Furuse
Journal: Liver Cancer
Liver Cancer (2024) 13 (2): 193–202.
https://doi.org/10.1159/000531820
Published Online: 07 July 2023
View article titled, Multicenter Phase II Trial of Lenvatinib plus Hepatic Intra-Arterial Infusion Chemotherapy with Cisplatin for Advanced Hepatocellular Carcinoma: LEOPARD
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Journal Articles

Attempt to Establish Prognostic Predictive System for Hepatocellular Carcinoma Using Artificial Intelligence for Assistance with Selection of Treatment Modality

Subject Area:
Gastroenterology , Oncology
Atsushi Hiraoka, Takashi Kumada, Toshifumi Tada, Hidenori Toyoda, Kazuya Kariyama, Takeshi Hatanaka, Satoru Kakizaki, Atsushi Naganuma, Ei Itobayashi, Kunihiko Tsuji, Toru Ishikawa, Hideko Ohama, Fujimasa Tada, Kazuhiro Nouso, On behalf of the Real-life Practice Experts for HCC (RELPEC) Study Group
Journal: Liver Cancer
Liver Cancer (2023) 12 (6): 565–575.
https://doi.org/10.1159/000530078
Published Online: 25 May 2023
View article titled, Attempt to Establish Prognostic Predictive System for Hepatocellular Carcinoma Using Artificial Intelligence for Assistance with Selection of Treatment Modality
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Journal Articles

Surgical Outcomes of Laparoscopic versus Open Hepatectomy for Left Hepatocellular Carcinoma: Propensity Score Analyses Using Retrospective Japanese and Korean Individual Patient Data

Subject Area:
Gastroenterology , Oncology
Masaki Kaibori, Kengo Yoshii, Yuzo Umeda, Takahito Yagi, Takehiro Okabayashi, Kenta Sui, Akira Mori, Yuhei Hamaguchi, Kiyoshi Kajiyama, Daisuke Hokuto, Kazuteru Monden, Tomoharu Yoshizumi, Yoriko Nomura, Kan Toriguchi, Jong Man Kim, Gi Hong Choi, Je Ho Ryu, Yangseok Koh, Koo Jeong Kang, Young Kyoung You, Kwang-Sik Chun, Young Seok Han, Chan Woo Cho, Young Il Choi, Dong-Sik Kim, Jae Do Yang, Keita Mori, Atsushi Hiraoka, Hiroki Yamaue, Masafumi Nakamura, Masakazu Yamamoto, Itaru Endo
Journal: Liver Cancer
Liver Cancer (2023) 12 (1): 32–43.
https://doi.org/10.1159/000527294
Published Online: 22 February 2023
View article titled, Surgical Outcomes of Laparoscopic versus Open Hepatectomy for Left Hepatocellular Carcinoma: Propensity Score Analyses Using Retrospective Japanese and Korean Individual Patient Data
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Journal Articles

Relationship of Atezolizumab plus Bevacizumab Treatment with Muscle Volume Loss in Unresectable Hepatocellular Carcinoma Patients: Multicenter Analysis

Subject Area:
Gastroenterology , Oncology
Atsushi Hiraoka, Takashi Kumada, Toshifumi Tada, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi, Shinya Fukunishi, Kunihiko Tsuji, Toru Ishikawa, Kazuto Tajiri, Hironori Ochi, Satoshi Yasuda, Hidenori Toyoda, Chikara Ogawa, Takashi Nishimura, Takeshi Hatanaka, Satoru Kakizaki, Noritomo Shimada, Kazuhito Kawata, Atsushi Naganuma, Masaki Kaibori, Takaaki Tanaka, Hideko Ohama, Kazuhiro Nouso, Asahiro Morishita, Akemi Tsutsui, Takuya Nagano, Norio Itokawa, Tomomi Okubo, Taeang Arai, Michitaka Imai, Yohei Koizumi, Shinichiro Nakamura, Kouji Joko, Hiroko Iijima, Hisashi Kosaka, Yoichi Hiasa, Masatoshi Kudo, On behalf of the Real-life Practice Experts for HCC (RELPEC) Study Group, HCC 48 Group (hepatocellular carcinoma experts from 48 clinics in Japan)
Journal: Liver Cancer
Liver Cancer (2023) 12 (3): 209–217.
https://doi.org/10.1159/000527402
Published Online: 08 December 2022
View article titled, Relationship of Atezolizumab plus Bevacizumab Treatment with Muscle Volume Loss in Unresectable Hepatocellular Carcinoma Patients: Multicenter Analysis
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Journal Articles

Real Life Study of Lenvatinib Therapy for Hepatocellular Carcinoma: RELEVANT Study

Subject Area:
Gastroenterology , Oncology
Andrea Casadei-Gardini, Margherita Rimini, Masatoshi Kudo, Shigeo Shimose, Toshifumi Tada, Goki Suda, Myung Ji Goh, Andre Jefremow, Mario Scartozzi, Giuseppe Cabibbo, Claudia Campani, Emiliano Tamburini, Francesco Tovoli, Kazuomi Ueshima, Tomoko Aoki, Hideki Iwamoto, Takuji Torimura, Takashi Kumada, Atsushi Hiraoka, Masanori Atsukawa, Ei Itobayashi, Hidenori Toyoda, Naoya Sakamoto, Takuya Sho, Wonseok Kang, Jürgen Siebler, Markus Friedrich Neurath, Valentina Burgio, Stefano Cascinu
Journal: Liver Cancer
Liver Cancer (2022) 11 (6): 527–539.
https://doi.org/10.1159/000525145
Published Online: 11 July 2022
View article titled, Real Life Study of Lenvatinib Therapy for Hepatocellular Carcinoma: RELEVANT Study
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Journal Articles

Management of Hepatocellular Carcinoma in Japan: JSH Consensus Statements and Recommendations 2021 Update

Subject Area:
Gastroenterology , Oncology
Masatoshi Kudo, Yusuke Kawamura, Kiyoshi Hasegawa, Ryosuke Tateishi, Kazuya Kariyama, Shuichiro Shiina, Hidenori Toyoda, Yasuharu Imai, Atsushi Hiraoka, Masafumi Ikeda, Namiki Izumi, Michihisa Moriguchi, Sadahisa Ogasawara, Yasunori Minami, Kazuomi Ueshima, Takamichi Murakami, Shiro Miyayama, Osamu Nakashima, Hirohisa Yano, Michiie Sakamoto, Etsuro Hatano, Mitsuo Shimada, Norihiro Kokudo, Satoshi Mochida, Tetsuo Takehara, HCC Expert Panel of the Japan Society of Hepatology
Journal: Liver Cancer
Liver Cancer (2021) 10 (3): 181–223.
https://doi.org/10.1159/000514174
Published Online: 19 May 2021
View article titled, Management of Hepatocellular Carcinoma in Japan: JSH Consensus Statements and Recommendations 2021 Update
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Journal Articles

What Can Be Done to Solve the Unmet Clinical Need of Hepatocellular Carcinoma Patients following Lenvatinib Failure?

Subject Area:
Gastroenterology , Oncology
Atsushi Hiraoka, Takashi Kumada, Toshifumi Tada, Kazuya Kariyama, Joji Tani, Shinya Fukunishi, Masanori Atsukawa, Masashi Hirooka, Kunihiko Tsuji, Toru Ishikawa, Koichi Takaguchi, Ei Itobayashi, Kazuto Tajiri, Noritomo Shimada, Hiroshi Shibata, Hironori Ochi, Kazuhito Kawata, Satoshi Yasuda, Hidenori Toyoda, Hideko Ohama, Kazuhiro Nouso, Akemi Tsutsui, Takuya Nagano, Norio Itokawa, Korenobu Hayama, Taeang Arai, Michitaka Imai, Yohei Koizumi, Shinichiro Nakamura, Kouji Joko, Kojiro Michitaka, Yoichi Hiasa, Masatoshi Kudo, RELPEC Study Group and HCC 48 Group
Journal: Liver Cancer
Liver Cancer (2021) 10 (2): 115–125.
https://doi.org/10.1159/000513355
Published Online: 25 February 2021
View article titled, What Can Be Done to Solve the Unmet Clinical Need of Hepatocellular Carcinoma Patients following Lenvatinib Failure?
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Journal Articles

EZ-ALBI Score for Predicting Hepatocellular Carcinoma Prognosis

Subject Area:
Gastroenterology , Oncology
Kazuya Kariyama, Kazuhiro Nouso, Atsushi Hiraoka, Akiko Wakuta, Ayano Oonishi, Teiji Kuzuya, Hidenori Toyoda, Toshifumi Tada, Kunihiko Tsuji, Ei Itobayashi, Toru Ishikawa, Koichi Takaguchi, Akemi Tsutsui, Noritomo Shimada, Masatoshi Kudo, Takashi Kumada, RELPEC Study Group and HCC 48 Group
Journal: Liver Cancer
Liver Cancer (2020) 9 (6): 734–743.
https://doi.org/10.1159/000508971
Published Online: 23 October 2020
View article titled, EZ-ALBI Score for Predicting Hepatocellular Carcinoma Prognosis
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Journal Articles

Complications after Radiofrequency Ablation for Hepatocellular Carcinoma: A Multicenter Study Involving 9,411 Japanese Patients

Subject Area:
Gastroenterology , Oncology
Masaki Maeda, Issei Saeki, Isao Sakaida, Hiroshi Aikata, Yasuyuki Araki, Chikara Ogawa, Kazuya Kariyama, Kazuhiro Nouso, Mikiya Kitamoto, Haruhiko Kobashi, Shuichi Sato, Hiroshi Shibata, Kouji Joko, Shintaro Takaki, Hiroyuki Takabatake, Akemi Tsutsui, Koichi Takaguchi, Tetsu Tomonari, Shinichiro Nakamura, Takakazu Nagahara, Atsushi Hiraoka, Tomomitsu Matono, Masahiko Koda, Mari Mandai, Tomohiko Mannami, Akeri Mitsuda, Takashi Moriya, Kazuhisa Yabushita, Joji Tani, Takahito Yagi, Takahiro Yamasaki
Journal: Liver Cancer
Liver Cancer (2020) 9 (1): 50–62.
https://doi.org/10.1159/000502744
Published Online: 22 October 2019
View article titled, Complications after Radiofrequency Ablation for Hepatocellular Carcinoma: A Multicenter Study Involving 9,411 Japanese Patients
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Journal Articles

Treatment of Intermediate-Stage Hepatocellular Carcinoma in Japan: Position of Curative Therapies

Subject Area:
Gastroenterology , Oncology
Kazuya Kariyama, Kazuhiro Nouso, Akiko Wakuta, Ayano Oonishi, Hidenori Toyoda, Toshifumi Tada, Atsushi Hiraoka, Kunihiko Tsuji, Ei Itobayashi, Toru Ishikawa, Koichi Takaguchi, Akemi Tsutsui, Noritomo Shimada, Takashi Kumada, on behalf of the Real-Life Practice Experts for HCC (RELPEC) Study Group and HCC 48 Group (Hepatocellular Carcinoma Experts from 48 Clinics)
Journal: Liver Cancer
Liver Cancer (2020) 9 (1): 41–49.
https://doi.org/10.1159/000502479
Published Online: 22 October 2019
View article titled, Treatment of Intermediate-Stage Hepatocellular Carcinoma in Japan: Position of Curative Therapies
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Journal Articles

Post-Progression Treatment Eligibility of Unresectable Hepatocellular Carcinoma Patients Treated with Lenvatinib

Subject Area:
Gastroenterology , Oncology
Atsushi Hiraoka, Takashi Kumada, Shinya Fukunishi, Masanori Atsukawa, Masashi Hirooka, Kunihiko Tsuji, Toru Ishikawa, Koichi Takaguchi, Kazuya Kariyama, Ei Itobayashi, Kazuto Tajiri, Noritomo Shimada, Hiroshi Shibata, Hironori Ochi, Toshifumi Tada, Hidenori Toyoda, Keisuke Yokohama, Kazuhiro Nouso, Akemi Tsutsui, Takuya Nagano, Norio Itokawa, Korenobu Hayama, Taeang Arai, Michitaka Imai, Kouji Joko, Yohei Koizumi, Yoichi Hiasa, Kojiro Michitaka, Masatoshi Kudo, On behalf of the Real-Life Practice Experts for HCC (RELPEC) Study Group and HCC 48 Group (hepatocellular carcinoma experts from 48 clinics in Japan)
Journal: Liver Cancer
Liver Cancer (2020) 9 (1): 73–83.
https://doi.org/10.1159/000503031
Published Online: 18 October 2019
View article titled, Post-Progression Treatment Eligibility of Unresectable Hepatocellular Carcinoma Patients Treated with Lenvatinib
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Journal Articles

Newly Proposed ALBI Grade and ALBI-T Score as Tools for Assessment of Hepatic Function and Prognosis in Hepatocellular Carcinoma Patients

Subject Area:
Gastroenterology , Oncology
Atsushi Hiraoka, Takashi Kumada, Kojiro Michitaka, Masatoshi Kudo
Journal: Liver Cancer
Liver Cancer (2019) 8 (5): 312–325.
https://doi.org/10.1159/000494844
Published Online: 10 October 2019
View article titled, Newly Proposed ALBI Grade and ALBI-T Score as Tools for Assessment of Hepatic Function and Prognosis in Hepatocellular Carcinoma Patients
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Journal Articles

Prediction of Prognosis of Intermediate-Stage HCC Patients: Validation of the Tumor Marker Score in a Nationwide Database in Japan

Subject Area:
Gastroenterology , Oncology
Atsushi Hiraoka, Kojiro Michitaka, Takashi Kumada, Namiki Izumi, Masumi Kadoya, Norihiro Kokudo, Shoji Kubo, Yutaka Matsuyama, Osamu Nakashima, Michiie Sakamoto, Tadatoshi Takayama, Takashi Kokudo, Kosuke Kashiwabara, Susumu Eguchi, Tatsuya Yamashita, Masatoshi Kudo, The Liver Cancer Study Group of Japan
Journal: Liver Cancer
Liver Cancer (2019) 8 (5): 403–411.
https://doi.org/10.1159/000495944
Published Online: 18 February 2019
View article titled, Prediction of Prognosis of Intermediate-Stage HCC Patients: Validation of the Tumor Marker Score in a Nationwide Database in Japan
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Journal Articles

Validation of Modified ALBI Grade for More Detailed Assessment of Hepatic Function in Hepatocellular Carcinoma Patients: A Multicenter Analysis

Subject Area:
Gastroenterology , Oncology
Atsushi Hiraoka, Takashi Kumada, Kunihiko Tsuji, Koichi Takaguchi, Ei Itobayashi, Kazuya Kariyama, Hironori Ochi, Kazuto Tajiri, Masashi Hirooka, Noritomo Shimada, Toru Ishikawa, Yoshihiko Tachi, Toshifumi Tada, Hidenori Toyoda, Kazuhiro Nouso, Kouji Joko, Yoichi Hiasa, Kojiro Michitaka, Masatoshi Kudo, on behalf of the RELPEC Study Group and HCC 48 Group
Journal: Liver Cancer
Liver Cancer (2019) 8 (2): 121–129.
https://doi.org/10.1159/000488778
Published Online: 11 June 2018
View article titled, Validation of Modified ALBI Grade for More Detailed Assessment of Hepatic Function in Hepatocellular Carcinoma Patients: A Multicenter Analysis
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Journal Articles

ALBI Score as a Novel Tool in Staging and Treatment Planning for Hepatocellular Carcinoma: Advantage of ALBI Grade for Universal Assessment of Hepatic Function

Subject Area:
Gastroenterology , Oncology
Atsushi Hiraoka, Kojiro Michitaka, Takashi Kumada, Masashi Kudo
Journal: Liver Cancer
Liver Cancer (2017) 6 (4): 377–379.
https://doi.org/10.1159/000481212
Published Online: 19 October 2017
View article titled, ALBI Score as a Novel Tool in Staging and Treatment Planning for Hepatocellular Carcinoma: Advantage of ALBI Grade for Universal Assessment of Hepatic Function
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Journal Articles

Validation and Potential of Albumin-Bilirubin Grade and Prognostication in a Nationwide Survey of 46,681 Hepatocellular Carcinoma Patients in Japan: The Need for a More Detailed Evaluation of Hepatic Function

Subject Area:
Gastroenterology , Oncology
Atsushi Hiraoka, Kojiro Michitaka, Takashi Kumada, Namiki Izumi, Masumi Kadoya, Norihiro Kokudo, Shoji Kubo, Yutaka Matsuyama, Osamu Nakashima, Michiie Sakamoto, Tadatoshi Takayama, Takashi Kokudo, Kosuke Kashiwabara, Masatoshi Kudo, The Liver Cancer Study Group of Japan
Journal: Liver Cancer
Liver Cancer (2017) 6 (4): 325–336.
https://doi.org/10.1159/000479984
Published Online: 22 September 2017
View article titled, Validation and Potential of Albumin-Bilirubin Grade and Prognostication in a Nationwide Survey of 46,681 Hepatocellular Carcinoma Patients in Japan: The Need for a More Detailed Evaluation of Hepatic Function
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Journal Articles

Albumin-Bilirubin (ALBI) Grade as Part of the Evidence-Based Clinical Practice Guideline for HCC of the Japan Society of Hepatology: A Comparison with the Liver Damage and Child-Pugh Classifications

Subject Area:
Gastroenterology , Oncology
Atsushi Hiraoka, Takashi Kumada, Masatoshi Kudo, Masashi Hirooka, Kunihiko Tsuji, Ei Itobayashi, Kazuya Kariyama, Toru Ishikawa, Kazuto Tajiri, Hironori Ochi, Toshifumi Tada, Hidenori Toyoda, Kazuhiro Nouso, Kouji Joko, Hideki Kawasaki, Yoichi Hiasa, Kojiro Michitaka, on behalf of the Real-Life Practice Experts for HCC (RELPEC) Study Group and HCC 48 Group (hepatocellular carcinoma experts from 48 clinics)
Journal: Liver Cancer
Liver Cancer (2017) 6 (3): 204–215.
https://doi.org/10.1159/000452846
Published Online: 01 March 2017
View article titled, Albumin-Bilirubin (ALBI) Grade as Part of the Evidence-Based Clinical Practice Guideline for HCC of the Japan Society of Hepatology: A Comparison with the Liver Damage and Child-Pugh Classifications
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